tetano
Editor, Senior Moderator
Indian J Virol. 2013 Jun;24(1):85-9. doi: 10.1007/s13337-012-0122-z. Epub 2013 Jan 13.
H1N1 influenza A virus Related Pneumonia and Respiratory Failure.
Okur M1, Erbey F2, Yazicioglu O3, Celik A4, Tukenmez B5, Sunnetcioglu M4, Gassaloglu M6, Acar MN2, Kaya A2.
Author information
Abstract
Influenza viruses are common respiratory pathogens in humans and can cause serious infection that leads to the development of pneumonia. In this study, the clinical and laboratory features of 36 patients from Turkey who are hospitalized in intensive care unit due to pandemic influenza A (H1N1) associated pneumonia and respiratory failure were retrospectively evaluated. The most common symptoms were cough and fever. Consolidation (36.1 %) and interstitial changes (30.6 %) were the most frequently identified findings on chest radiographs at the time of admission. Six of the patients (16.7 %) died. Mortality occurred in 3 of 13 patients (23.1 %) with underlying disease, whilst it occurred in only 3 of 23 patients (13 %) who were previously healthy. Mortality was found to be significantly associated only with an elevated lactate dehydrogenase level. A significant relationship was determined only between the presence of lymphopenia and acute respiratory distress syndrome and the need for intensive care treatment. The average time elapsed from the onset of the symptoms until admission was 8.67 ? 2.87 days for the patients died, and 6.0 ? 3.8 days for the patients survived.
KEYWORDS:
H1N1, Pneumonia, Respiratory failure, Swine influenza virus
PMID:
24426265
[PubMed]
PMCID:
PMC3650195
[Available on 2014/6/1]
http://www.ncbi.nlm.nih.gov/pubmed/24426265
H1N1 influenza A virus Related Pneumonia and Respiratory Failure.
Okur M1, Erbey F2, Yazicioglu O3, Celik A4, Tukenmez B5, Sunnetcioglu M4, Gassaloglu M6, Acar MN2, Kaya A2.
Author information
Abstract
Influenza viruses are common respiratory pathogens in humans and can cause serious infection that leads to the development of pneumonia. In this study, the clinical and laboratory features of 36 patients from Turkey who are hospitalized in intensive care unit due to pandemic influenza A (H1N1) associated pneumonia and respiratory failure were retrospectively evaluated. The most common symptoms were cough and fever. Consolidation (36.1 %) and interstitial changes (30.6 %) were the most frequently identified findings on chest radiographs at the time of admission. Six of the patients (16.7 %) died. Mortality occurred in 3 of 13 patients (23.1 %) with underlying disease, whilst it occurred in only 3 of 23 patients (13 %) who were previously healthy. Mortality was found to be significantly associated only with an elevated lactate dehydrogenase level. A significant relationship was determined only between the presence of lymphopenia and acute respiratory distress syndrome and the need for intensive care treatment. The average time elapsed from the onset of the symptoms until admission was 8.67 ? 2.87 days for the patients died, and 6.0 ? 3.8 days for the patients survived.
KEYWORDS:
H1N1, Pneumonia, Respiratory failure, Swine influenza virus
PMID:
24426265
[PubMed]
PMCID:
PMC3650195
[Available on 2014/6/1]
http://www.ncbi.nlm.nih.gov/pubmed/24426265