tetano
Editor, Senior Moderator
Front Neurol
. 2022 Aug 29;13:995875.
doi: 10.3389/fneur.2022.995875. eCollection 2022.
Atypical acute disseminated encephalomyelitis with systemic inflammation after a first dose of AztraZaneca COVID-19 vaccine. A case report
Laure Bastide[SUP] 1 [/SUP], Gaetano Perrotta[SUP] 1 [/SUP], Valentina Lolli[SUP] 2 [/SUP], Céline Mathey[SUP] 3 [/SUP], Ortensa-Irina Vierasu[SUP] 3 [/SUP], Serge Goldman[SUP] 3 [/SUP], Frédéric Vandergheynst[SUP] 4 [/SUP]
Affiliations
Abstract
Background: Only a few cases of acute disseminated encephalomyelitis (ADEM) following coronavirus disease 19 (COVID-19) vaccination have been described since the beginning of the vaccination campaign.
Results: Here we report the first case of central nervous system (CNS) demyelination with systemic inflammatory findings on whole body 19-fluorodeoxyglucose positron emission tomography with computed tomography (FDG-PET/CT) following the ChAdOx1 nCoV-19 vaccine.
Conclusions: Clinicians should stay aware of potential new adverse events after immunization.
Keywords: COVID-19; acute disseminated encephalomyelitis (ADEM); fluorodeoxyglucose positron emission tomography with computed tomography (FDG-PET/CT); systemic inflammation; vaccination.
. 2022 Aug 29;13:995875.
doi: 10.3389/fneur.2022.995875. eCollection 2022.
Atypical acute disseminated encephalomyelitis with systemic inflammation after a first dose of AztraZaneca COVID-19 vaccine. A case report
Laure Bastide[SUP] 1 [/SUP], Gaetano Perrotta[SUP] 1 [/SUP], Valentina Lolli[SUP] 2 [/SUP], Céline Mathey[SUP] 3 [/SUP], Ortensa-Irina Vierasu[SUP] 3 [/SUP], Serge Goldman[SUP] 3 [/SUP], Frédéric Vandergheynst[SUP] 4 [/SUP]
Affiliations
- PMID: 36105772
- PMCID: PMC9465085
- DOI: 10.3389/fneur.2022.995875
Abstract
Background: Only a few cases of acute disseminated encephalomyelitis (ADEM) following coronavirus disease 19 (COVID-19) vaccination have been described since the beginning of the vaccination campaign.
Results: Here we report the first case of central nervous system (CNS) demyelination with systemic inflammatory findings on whole body 19-fluorodeoxyglucose positron emission tomography with computed tomography (FDG-PET/CT) following the ChAdOx1 nCoV-19 vaccine.
Conclusions: Clinicians should stay aware of potential new adverse events after immunization.
Keywords: COVID-19; acute disseminated encephalomyelitis (ADEM); fluorodeoxyglucose positron emission tomography with computed tomography (FDG-PET/CT); systemic inflammation; vaccination.