tetano
Editor, Senior Moderator
Front Cardiovasc Med
. 2021 Feb 2;8:636843.
doi: 10.3389/fcvm.2021.636843. eCollection 2021.
Microvascular Angiopathic Consequences of COVID-19
Margaret Nalugo[SUP] 1 [/SUP], Linda J Schulte[SUP] 2 [/SUP], Muhammad F Masood[SUP] 2 [/SUP], Mohamed A Zayed[SUP] 1 3 4 5 [/SUP]
Affiliations
Abstract
The coronavirus disease-2019 (COVID-19) pandemic has rapidly spread across the world. The disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which first appeared in Wuhan, China in December, 2019. Ever increasing data is continuing to emerge about the impact of COVID-19 on cardiovascular tissue and other organ system. Clinical features associated with COVID-19 suggest that endothelial cell dysfunction and microvascular thrombosis are to a large extent contributing to resultant multi-organ complications. This review is aimed at highlighting the critical aspects associated with COVID-19 and its presumed microvascular angiopathic consequences on the cardiovascular system leading to multi-organ dysfunction.
Keywords: COVID-19; angiopathy; cardiac dysfunction; micovascular disease; vascular thrombosis.
. 2021 Feb 2;8:636843.
doi: 10.3389/fcvm.2021.636843. eCollection 2021.
Microvascular Angiopathic Consequences of COVID-19
Margaret Nalugo[SUP] 1 [/SUP], Linda J Schulte[SUP] 2 [/SUP], Muhammad F Masood[SUP] 2 [/SUP], Mohamed A Zayed[SUP] 1 3 4 5 [/SUP]
Affiliations
- PMID: 33604359
- PMCID: PMC7884319
- DOI: 10.3389/fcvm.2021.636843
Abstract
The coronavirus disease-2019 (COVID-19) pandemic has rapidly spread across the world. The disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which first appeared in Wuhan, China in December, 2019. Ever increasing data is continuing to emerge about the impact of COVID-19 on cardiovascular tissue and other organ system. Clinical features associated with COVID-19 suggest that endothelial cell dysfunction and microvascular thrombosis are to a large extent contributing to resultant multi-organ complications. This review is aimed at highlighting the critical aspects associated with COVID-19 and its presumed microvascular angiopathic consequences on the cardiovascular system leading to multi-organ dysfunction.
Keywords: COVID-19; angiopathy; cardiac dysfunction; micovascular disease; vascular thrombosis.