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France - Family pet tests for monkeypox as first human-to-dog transmission case confirmed

Shiloh

Editor, Senior Moderator
Source: https://www.mirror.co.uk/news/health/family-pet-tests-monkeypox-first-27724370


Experts have confirmed the first case of a dog with confirmed monkeypox virus infection in Paris, France that may have been acquired through human transmission - a family pet tested positive for the virus 12 days after its owners began to show symptoms
The men had been co-sleeping with their dog before it tested positive for monkeyvirus
ByPaige Freshwater Content Editor
12:24, 12 Aug 2022Updated12:28, 12 Aug 2022

A family dog has tested positive for monkeypox virus in what may be the first human-to-dog transmission case ever recorded. Researchers raised the alarm after an Italian greyhound contracted the virus 12 days after its owners began to show their onset symptoms.

Two men attended Pitié-Salpêtrière Hospital, in Paris, France, on June 10, after developing anal ulceration six days after having sex. One man had been experiencing anal ulceration and a rash on his face, ears, and legs, while the other developed a rash just on his legs and back.

In both cases, the men experienced fatigue, headaches, and a fever four days after breaking out in a rash.

They had been co-sleeping with their dog - but said they have have been "careful to prevent their dog from contact with other pets or humans from the onset of their own symptoms".

Despite their efforts, their dog tested positive for monkeypox virus after presenting "mucocutaneous lesions, including abdomen pustules and a thin anal ulceration".

New research, published on The Lancet, a weekly peer-reviewed general medical journal, reads: "On July 23, 2022, monkeypox was declared a Public Health Emergency of International Concern by WHO Director-General Tedros Adhanom Ghebreyesus...
 
First possible case of human-to-dog monkeypox transmission 'not surprising,' WHO says

Naomi Thomas
...
Published Aug. 16, 2022 1:15 p.m. CST

The first possible case of human-to-dog transmission of monkeypox -- recently reported in a couple and their pet in Paris -- had been a theoretical risk up till now, said Dr. Rosamund Lewis, technical lead on the monkeypox response for the World Health Organization.
...
NEW, BUT NOT SURPRISING, INFORMATION, WHO SAYS
Lewis said that previously, only animal-to-human transmission of the virus was reported, referencing a monkeypox outbreak in the U.S. in which people were infected with the virus through pet prairie dogs.

"This is the first incident that we're learning about where there is human-to-animal transmission," Lewis said during a Washington Post Live event on Monday. "This has not been reported before, and it has not been reported that dogs have been infected before.

"On a number of levels, this is new information," she said. "It's not surprising information, and it's something that we've been on the watch out for."

She noted that within WHO, experts have been working with partners such as the World Organization of Animal Health and the Food and Agriculture Organization to address the issue.

"The messaging that has been given up until now is that pets should be isolated from the family members who may be infected," she said. "This has been an example of precautionary approach, precautionary messaging, because we didn't have the information that this had ever happened before, it had not been reported before, but it was a reasonable, cautious message to give. And now we have the first incident where this has actually occurred."

Lewis said it isn't clear whether the infected dog will be able to transmit the virus back to humans. But sometimes, even when they don't have all the evidence, public health profesionals have to figure out the most useful messaging that will allow people to appreciate their level of risk.

"This is an example where most pets will not be at risk, it may only be those who are actually in the household of someone who's infected," she said.

...
https://www.ctvnews.ca/health/first...ransmission-not-surprising-who-says-1.6029468
 
Translation Google


In Paris, the first dog infected with monkeypox did not develop the disease

The greyhound who contracted the monkey pox virus in Paris was only a healthy carrier and did not develop the disease, but vigilance is still required.

The dog that tested positive for the monkeypox virus in Paris ultimately did not develop the disease, confirms the co-author of the study published in The Lancet, Christophe Cordevant.

By Maud Guilbeault
Published on Aug 24 '22 at 6:09 PM

On August 10, 2022, a study published in the scientific journal The Lancet confirmed the contamination of a dog by the monkey pox virus in Paris . Infected after having slept with his masters, this is the first proven case of transmission from human beings to animals.

After additional analyzes carried out jointly by, in particular, ANSES (National Agency for Food, Environmental and Occupational Health Safety) and the Pitié-Salpêtrière hospital, it was finally found that had not developed the disease and was only a healthy carrier .

No existing data on monkeypox in dogs

“We have carried out additional investigations ”, specifies to actu Paris Christophe Cordevant , scientific adviser at ANSES and co-author of the study published in The Lancet . Twenty days after the return of the positive PCR test from the four-year-old Italian greyhound, “new samples were taken, in particular a serological test to find out if there had been an immune response directed against the virus”.

And the results are formal according to the scientist: since there was no trace of an immune response, “there was no disease”.

However, he carried lesions like his masters. A coincidence that can be explained, for Christophe Cordevant, by the fact that “this type of short-haired dog can hurt itself by scratching . The difficulty is that we have no idea what the lesions associated with the disease look like in dogs, since nothing has ever been described. »

“It is very important to isolate yourself”

At this stage, the only animals known to be able to develop the disease are rodents, thanks to " previous investigations carried out during the epidemic episode that occurred in the United States in 2003", specifies Christophe Cordevant. Chinchillas and prairie dogs, in particular, had then contracted monkey pox.

Concerning our pets - except rodents -, there is therefore currently no data that demonstrates that they can develop the disease and its symptoms . Christophe Cordevant recalls, however, that a dog carrying the virus, as was the case with the greyhound discovered in Paris, could hypothetically be a vector of the disease between two humans.

"We must remain vigilant", supports the scientific adviser, recalling the instructions issued by ANSES at the beginning of June. “It is very important to isolate yourself from other members of the household and from animals, as soon as you know you are positive and/or you observe lesions suggesting a Monkeypox infection”, he continues. . A recommendation relayed by the World Health Organization (WHO) shortly after the contamination of the Italian greyhound.

https://actu.fr/ile-de-france/paris...ge-n-a-pas-developpe-la-maladie_53332527.html


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06/16/2022—expertise


ANIMAL HEALTH AND WELFARE


Monkey pox: what is the risk of spreading to pets?

Cats, dogs, rodents…to which pets can humans transmit monkeypox? Following the increase in the number of people infected with this virus in many countries outside endemic areas, including France, ANSES received an urgent request on this issue.


The animal species most at risk of contamination by humans

Monkeypox virus (MPXV) or monkey pox is an endemic zoonosis in Central and West Africa, where the virus has been demonstrated in various wild animal species without the reservoir having been formally identified.

In the available scientific literature, data relating to the susceptibility of pets to monkeypox are very limited or even absent. The Agency therefore stresses that the conclusions of its expert appraisal are likely to change.

In the state of knowledge:
  1. lagomorphs, such as rabbits or hares , are receptive and sensitive under experimental conditions, especially baby rabbits. These are the most represented animals among the new pets;
  2. the sciurids, including squirrels and prairie dogs, seem to constitute a receptive and sensitive family, possibly the most at risk of contamination by humans. However, the possession and sale of these animals is not authorized in France;
  3. pet rodents , such as brown rats, mice, guinea pigs or even hamsters, seem not very receptive to the virus in adulthood but could be so for the youngest animals;
  4. data are lacking for ferrets and dogs. Concerning cats, only one serological study exists with negative results. At this stage, no clinical cases have been reported in these three species.

Suspicion of transmission of the virus to the dog

Since the expertise published by the Agency on June 16, 2022, a suspicion of transmission of the Monkeypox virus from humans to a dog has been recorded. If the dog was indeed a carrier of the virus, it did not develop the disease as shown by the negative serological test.



Recommendations to limit the spread of the virus to pets

When a person is infected with the monkeypox virus, the precautionary measures include:
  1. avoid contact between the animal and the infected person as much as possible , ideally by having the animal looked after by another person during the isolation period;
  2. before each contact with your animal, wash your hands, then wear disposable gloves and a mask.
These recommendations may be refined based on new data.

Pending additional data on the sensitivity and receptivity of pets, the greatest vigilance is recommended to veterinarians receiving in consultation animals whose owner is symptomatic. This will help detect any early signs of the virus passing from human to animal. This will require organizing a monitoring program involving field veterinarians.


A new expertise to come

By the end of 2022, new expertise will complete these initial elements. It will focus on the assessment of the risks of transmission of the virus to peridomestic fauna (particularly rodents) and to the environment as well as the measures to be taken to prevent and monitor it. An assessment of the risk of virus importation by infected animals will also be carried out.



https://www.anses.fr/fr/content/variole-du-singe-quel-risque-de-diffusion-aux-animaux-de-compagnie
 
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