tetano
Editor, Senior Moderator
J Nat Prod. 2015 Apr 30. [Epub ahead of print]
[h=1]Flavonoids from Matteuccia struthiopteris and Their Anti-influenza Virus (H1N1) Activity.[/h] Li B[SUP]1,[/SUP][SUP]2[/SUP], Ni Y[SUP]1[/SUP], Zhu LJ[SUP]1[/SUP], Wu FB[SUP]3[/SUP], Yan F[SUP]1[/SUP], Zhang X[SUP]1,[/SUP][SUP]4[/SUP], Yao XS[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Seven new flavonoid glycosides (1-7), matteflavosides A-G, together with 12 known flavonoids (8-19) were isolated from the rhizomes of Matteuccia struthiopteris (L.) Todar. Their structures were established via the analyses of extensive spectroscopic data. All compounds were evaluated for their anti-influenza virus (H1N1) activity using the neuraminidase inhibition assay. The results showed that compound 7 exhibited significant inhibitory activity against the H1N1 influenza virus neuraminidase with an EC[SUB]50[/SUB] value of 6.8 ? 1.1 μM and an SI value of 34.4, and compounds 8 and 17 showed moderate inhibitory activity.
PMID: 25927664 [PubMed - as supplied by publisher]
[h=1]Flavonoids from Matteuccia struthiopteris and Their Anti-influenza Virus (H1N1) Activity.[/h] Li B[SUP]1,[/SUP][SUP]2[/SUP], Ni Y[SUP]1[/SUP], Zhu LJ[SUP]1[/SUP], Wu FB[SUP]3[/SUP], Yan F[SUP]1[/SUP], Zhang X[SUP]1,[/SUP][SUP]4[/SUP], Yao XS[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Seven new flavonoid glycosides (1-7), matteflavosides A-G, together with 12 known flavonoids (8-19) were isolated from the rhizomes of Matteuccia struthiopteris (L.) Todar. Their structures were established via the analyses of extensive spectroscopic data. All compounds were evaluated for their anti-influenza virus (H1N1) activity using the neuraminidase inhibition assay. The results showed that compound 7 exhibited significant inhibitory activity against the H1N1 influenza virus neuraminidase with an EC[SUB]50[/SUB] value of 6.8 ? 1.1 μM and an SI value of 34.4, and compounds 8 and 17 showed moderate inhibitory activity.
PMID: 25927664 [PubMed - as supplied by publisher]