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First Northern Kentucky Flu Death

Re: First Northern Kentucky Flu Death

pH1N1 Child Vaccine Escape
CDC Early 2013


<div style="text-align: center;">
<hr style="width: 30%;" />41 Cases over 43 Sequences<hr style="width: 30%;" /></div>
Introduction

In the 30 days covering 2013-02-28 to 2013-03-29, the <span style="color: #783f04;"><b>United States CDC</b></span> released a total of 43 <b><span style="color: #632423; font-family: "Trebuchet MS";">pH1N1</span></b> sequences at <strong>GISAID </strong>on 41 human cases<strong> </strong>sampled from October 2012 to February 2013. Geographic surveillance includes <b>America,</b> <b>Africa, Asia </b>and<b> Russia. </b>Although <b><span style="color: #632423; font-family: "Trebuchet MS";">pH1N1</span></b> in most locales during the 2012-2013 season was the <b><span style="color: #783f04;">minority</span></b> serotype, the sequences in this Analytic Report describe a high level of human-infective diversity and an ease of avian genetic acquisition, including multiple instances demonstrating concentrated transport of <b><span style="color: #660000;">High-CFR</span></b> <b><span style="color: #632423; font-family: "Trebuchet MS";">pH1N1 </span><span style="color: #783f04;">Upsilon</span></b> polymorphisms onto single sequences.

. . .

Read the Open-Access, Full-Text
Investigational Analytic
including Genetic Details​
 
Re: First Northern Kentucky Flu Death

Kentucky pH1N1
Genetic Features

  • Novelty
    • Novel Hemagglutinin
    • Novel Neuraminidase
  • H7N9 Correlation
    • HA #2L
    • NA 199N
    • NA 313H
  • Vaccine Escape Polymorphism Correlation
    • NA 128G mix wt correlated to HA 156E & HA 157E
  • Drug Resistance Polymorphism Correlation
    • NA 128G mix wt correlated to NA 275Y

. . .

Read the Open-Access, Full-Text
Investigational Analytic
including Genetic Details​
 
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