Mary Wilson
Well-known member
March 23, 2023, 8:41pm
mmdiagne
On February 7th, 2023, an alert was given by the Ministry of Health in the district of Kie Ntem province, in eastern Equatorial Guinea. Several patients presented with symptoms suggestive of hemorrhagic fever, and a mortality cluster (n=9 deaths) was finally reported. An additional eight blood samples were collected from other contacts and sent to the regional WHO reference center for arboviruses and hemorrhagic fever viruses at the Institut Pasteur de Dakar (IPD), Senegal.
On February 12th, 2023, the samples were received by IPD team to carry out the molecular diagnostic targeting several hemorrhagic fever viruses. One of the blood samples was taken from a suspected case that was confirmed positive for Marburg virus (MARV). The diagnostic result was communicated to the stakeholders less than one day after sample reception.
An amplicon-based sequencing approach was undertaken using new designed MARV-specific primers and a close to complete whole genome was obtained with 98.1% coverage (compared to the reference genome NC_001608). ...
https://virological.org/t/first-emergence-of-marburg-virus-in-equatorial-guinea-2023/924
mmdiagne
On February 7th, 2023, an alert was given by the Ministry of Health in the district of Kie Ntem province, in eastern Equatorial Guinea. Several patients presented with symptoms suggestive of hemorrhagic fever, and a mortality cluster (n=9 deaths) was finally reported. An additional eight blood samples were collected from other contacts and sent to the regional WHO reference center for arboviruses and hemorrhagic fever viruses at the Institut Pasteur de Dakar (IPD), Senegal.
On February 12th, 2023, the samples were received by IPD team to carry out the molecular diagnostic targeting several hemorrhagic fever viruses. One of the blood samples was taken from a suspected case that was confirmed positive for Marburg virus (MARV). The diagnostic result was communicated to the stakeholders less than one day after sample reception.
An amplicon-based sequencing approach was undertaken using new designed MARV-specific primers and a close to complete whole genome was obtained with 98.1% coverage (compared to the reference genome NC_001608). ...
https://virological.org/t/first-emergence-of-marburg-virus-in-equatorial-guinea-2023/924