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Fetal Pediatr Pathol. Vertical Transmission of Coronavirus Disease 19 (COVID-19) from Infected Pregnant Mothers to Neonates: A Review

tetano

Editor, Senior Moderator
Fetal Pediatr Pathol. 2020 Apr 2:1-5. doi: 10.1080/15513815.2020.1747120. [Epub ahead of print]
Vertical Transmission of Coronavirus Disease 19 (COVID-19) from Infected Pregnant Mothers to Neonates: A Review.


Karimi-Zarchi M[SUP]1,[/SUP][SUP]2[/SUP], Neamatzadeh H[SUP]3,[/SUP][SUP]4[/SUP], Dastgheib SA[SUP]5[/SUP], Abbasi H[SUP]6[/SUP], Mirjalili SR[SUP]4,[/SUP][SUP]7[/SUP], Behforouz A[SUP]6[/SUP], Ferdosian F[SUP]7,[/SUP][SUP]8[/SUP], Bahrami R[SUP]9[/SUP].

Author information




Abstract

Background: Since early December 2019, the Coronavirus Disease 19 (COVID-19) infection has been prevalent in China and eventually spread to other countries. There are a few published cases of COVID-19 occurring during pregnancy and due the possibility of mother-fetal vertical transmission, there is a concern that the fetuses may be at risk of congenital COVID-19. Methods: We reviewed the risk of vertical transmission of COVID-19 to the fetus of infected mothers by using data of published articles or official websites up to March 4, 2020. Results: A total of 31 infected pregnant mothers with COVID-19 were reported. No COVID-19 infection was detected in their neonates or placentas. Two mothers died from COVID-19-related respiratory complications after delivery. Conclusions: Currently, based on limited data, there is no evidence for intrauterine transmission of COVID-19 from infected pregnant women to their fetuses. Mothers may be at increased risk for more severe respiratory complications.



KEYWORDS:

COVID-19; Corona Virus; neonate; placenta; pregnant mothers; vertical transmission


PMID:32238084DOI:10.1080/15513815.2020.1747120
 
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