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Extracorporeal membrane oxygenation support in individuals with thoracic insufficiency

tetano

Editor, Senior Moderator
Perfusion. 2018 May 1:267659118778173. doi: 10.1177/0267659118778173. [Epub ahead of print]
[h=1]Extracorporeal membrane oxygenation support in individuals with thoracic insufficiency.[/h] Hancock S[SUP]1[/SUP], Froehlich C[SUP]2[/SUP], Armijo-Garcia V[SUP]3[/SUP], Meyer AD[SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]INTRODUCTION:[/h] Respiratory failure is the leading cause of mortality in individuals with congenital spine and rib deformities. We present a case report of a child with Jeune syndrome surviving respiratory failure using extracorporeal membrane oxygenation (ECMO). We also summarize thoracic insufficiency syndrome cases reported in the Extracorporeal Life Support Organization (ELSO) registry.
[h=4]CASE REPORT:[/h] A two-year-old male with a chest circumference less than a third percentile for age was admitted with influenza pneumonia developing a peak oxygenation index of 103.5. The child survived to baseline pulmonary function after nine days of venous-arterial ECMO support.
[h=4]DISCUSSION:[/h] The ELSO registry contained 27 individuals with a surrogate diagnosis of thoracic insufficiency (0.05%). There was no significant difference in survival to discharge for thoracic insufficiency patients (52%) compared to a previously healthy population supported with ECMO.
[h=4]CONCLUSION:[/h] ECMO is safe and may be effective in supporting individuals with thoracic insufficiency.


[h=4]KEYWORDS:[/h] Jeune syndrome; extracorporeal membrane oxygenation; pediatrics; thoracic insufficiency; thoracic surgery

PMID: 29792118 DOI: 10.1177/0267659118778173
 
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