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Evaluation of two avian influenza type A rapid antigen tests under Indonesian field conditions -J Vet Diagn Invest

Giuseppe

Giuseppe

Emeritus
J Vet Diagn Invest. 2008 Sep;20(5):642-4.

Evaluation of two avian influenza type A rapid antigen tests under Indonesian field conditions.
Loth L, Prijono WB, Wibawa H, Usman TB.

Food and Agricultural Organization of the United Nations, Menara Thamrin 7th Floor, Jl. M.H. Thamrin Kav. 3, Jakarta 10250, Indonesia. leo.loth@fao.org.

The current study evaluated the test characteristics of 2 commercially available rapid antigen tests for highly pathogenic avian influenza.

Diagnostic specimens were collected from free-ranging village chickens in Indonesia.

A total of 174 healthy, sick, and dead birds were included in the study.

The relative diagnostic test sensitivity and the relative diagnostic test specificity were calculated by using real-time reverse transcription polymerase chain reaction (RT-PCR) as the confirmatory diagnosis.

The AnigenR Rapid AIV Ag test had a relative diagnostic sensitivity of 0.69 (95% confidence interval [CI]: 0.56-0.80) and a relative diagnostic specificity of 0.98 (95% CI: 0.93-0.99).

The Flu Detect(TM) Antigen Capture test strip had a relative diagnostic sensitivity of 0.71 (95% CI: 0.58-0.82) and a relative diagnostic specificity of 0.98 (95% CI: 0.93-0.99).

These tests are a valuable tool for the Indonesian avian influenza control program by reliably and quickly detecting Influenza A virus from oropharyngeal swabs from sick or dying chickens.

PMID: 18776101 [PubMed - in process
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http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
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Re: J Vet Diagn Invest. Evaluation of two avian influenza type A rapid antigen tests under Indonesian field conditions.

Re: J Vet Diagn Invest. Evaluation of two avian influenza type A rapid antigen tests under Indonesian field conditions.

Interesting, we used to hear `rapid tests` had a reliability of no more than50%, this seems a lot better.

Lately we hear about using these or similar tests for human patients, it would be interesting to learn about results from these tests.
 
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