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Evaluation of the rapid influenza detection tests "GOLD SIGN FLU?" and "Quick Navi-Flu?" for detecting influenza viruses A and B antigens in adults du

tetano

Editor, Senior Moderator
Int J Infect Dis. 2016 Oct 6. pii: S1201-9712(16)31185-7. doi: 10.1016/j.ijid.2016.10.002. [Epub ahead of print]
[h=1]Evaluation of the rapid influenza detection tests "GOLD SIGN FLU?" and "Quick Navi-Flu?" for detecting influenza viruses A and B antigens in adults during the influenza season.[/h] Akaishi Y[SUP]1[/SUP], Matsumoto T[SUP]2[/SUP], Harada Y[SUP]3[/SUP], Hirayama Y[SUP]3[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] As the characteristics and accuracy of rapid influenza detection tests (RIDTs) vary, the development of a high-performance RIDT has been eagerly anticipated. In this study, we evaluated the new RIDT "GOLD SIGN FLU[SUP]?[/SUP]" and the usual RIDT "Quick Navi-Flu[SUP]?[/SUP]" in terms of detecting the influenza viruses A and B antigens in Japanese adults with influenza-like symptoms from December 2013 to March 2014. Among the 123 patients in whom nasopharyngeal swab specimens were collected, 59 tested positive (influenza A, 38; influenza B, 21) by viral isolation as the gold standard method. For "GOLD SIGN FLU[SUP]?[/SUP]", the sensitivities were 73.7% and 81.0%, and the specificities were 97.6% and 98.0% for influenza A and B, respectively. For "Quick Navi-Flu[SUP]?[/SUP]", the sensitivities were 86.8% and 85.7%, and the specificities were 98.8% and 100% for influenza A and B, respectively. More than 90% of the resulting line appearance time was less than 3minutes for influenza A and less than 2minutes for influenza B on the test strip of both RIDTs. "GOLD SIGN FLU[SUP]?[/SUP]" was useful for diagnosing influenza A, and the result was readily available for influenza B particularly among adult patients. "Quick Navi-Flu[SUP]?[/SUP]" showed better sensitivities and specificities than "GOLD SIGN FLU[SUP]?[/SUP]".
Copyright ? 2016. Published by Elsevier Ltd.


[h=4]KEYWORDS:[/h] Influenza; Rapid influenza detection test; Viral isolation

PMID: 27720945 DOI: 10.1016/j.ijid.2016.10.002
[PubMed - as supplied by publisher] Free full text
 
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