Eurosurv. Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care: I-MOVE-COVID-19 project, E

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• Esther Kissling[SUP]1[/SUP] , Mariette Hooiveld[SUP]2[/SUP] , Virginia Sandonis Martín[SUP]3[/SUP] , Iván Martínez-Baz[SUP]4,5[/SUP] , Naoma William[SUP]6[/SUP] , Ana-Maria Vilcu[SUP]7[/SUP] , Clara Mazagatos[SUP]5,8[/SUP] , Lisa Domegan[SUP]9[/SUP] , Simon de Lusignan[SUP]10,11[/SUP] , Adam Meijer[SUP]12[/SUP] , Ausenda Machado[SUP]13[/SUP] , Mia Brytting[SUP]14[/SUP] , Itziar Casado[SUP]4,5[/SUP] , Josephine-L K. Murray[SUP]6[/SUP] , Sylvie Belhillil[SUP]15,16[/SUP] , Amparo Larrauri[SUP]5,8[/SUP] , Joan O’Donnell[SUP]9[/SUP] , Ruby Tsang[SUP]10,11[/SUP] , Marit de Lange[SUP]12[/SUP] , Ana Paula Rodrigues[SUP]13[/SUP] , Maximilian Riess[SUP]14[/SUP] , Jesús Castilla[SUP]4,5[/SUP] , Mark Hamilton[SUP]6[/SUP] , Alessandra Falchi[SUP]17[/SUP] , Francisco Pozo[SUP]3[/SUP] , Linda Dunford[SUP]18[/SUP] , Jade Cogdale[SUP]19[/SUP] , Tessa Jansen[SUP]2[/SUP] , Raquel Guiomar[SUP]13[/SUP] , Theresa Enkirch[SUP]14[/SUP] , Cristina Burgui[SUP]4,5[/SUP] , Debbie Sigerson[SUP]6[/SUP] , Thierry Blanchon[SUP]7[/SUP] , Eva María Martínez Ochoa[SUP]20[/SUP] , Jeff Connell[SUP]18[/SUP] , Joanna Ellis[SUP]19[/SUP] , Rianne van Gageldonk-Lafeber[SUP]12[/SUP] , Irina Kislaya[SUP]13[/SUP] , Angela MC Rose[SUP]1[/SUP] , Marta Valenciano[SUP]1[/SUP] , I-MOVE-COVID-19 primary care study team[SUP]21[/SUP]

We measured COVID-19 vaccine effectiveness (VE) against symptomatic SARS-CoV-2 infection at primary care/outpatient level among adults ≥ 65 years old using a multicentre test-negative design in eight European countries. We included 592 SARS-CoV-2 cases and 4,372 test-negative controls in the main analysis. The VE was 62% (95% CI: 45–74) for one dose only and 89% (95% CI: 79–94) for complete vaccination. COVID-19 vaccines provide good protection against COVID-19 presentation at primary care/outpatient level, particularly among fully vaccinated individuals.

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https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2021.26.29.2100670#abstract_content