Eurosurv. Omicron BA.2.75 variant is efficiently neutralised following BA.1 and BA.5 breakthrough infection in vaccinated individuals, Israel, June to

[tetano]

• Nofar Atari[SUP]1,*[/SUP] , Limor Kliker[SUP]1,2,*[/SUP] , Neta Zuckerman[SUP]1,2[/SUP] , Bayan Abd Elkader[SUP]1[/SUP] , Yael Weiss-Ottolenghi[SUP]3[/SUP] , Ella Mendelson[SUP]1,2[/SUP] , Yitshak Kreiss[SUP]3[/SUP] , Gili Regev-Yochay[SUP]2,3,**[/SUP] , Michal Mandelboim[SUP]1,2,**[/SUP]

We evaluated neutralising antibody titres against wild type (WT) SARS-CoV-2 and four Omicron variants (BA.1, BA.2, BA.5 and BA.2.75) in fully vaccinated (three doses of Comirnaty vaccine) healthcare workers (HCW) in Israel who had breakthrough BA.1/BA5 infections. Omicron breakthrough infections in vaccinated individuals resulted in increased neutralising antibodies against the WT and Omicron variants compared with vaccinated uninfected HCW. HCW who recovered from BA.1 or BA.5 infections showed similar neutralising antibodies levels against BA.2.75.


https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2022.27.44.2200785