Eurosurv. Antibodies to SARS-CoV-2 protect against re-infection during outbreaks in care homes, September and October 2020

[tetano]

• Antibodies to SARS-CoV-2 protect against re-infection during outbreaks in care homes, September and October 2020
• Anna Jeffery-Smith[SUP]1[/SUP] , Nalini Iyanger[SUP]2[/SUP] , Sarah V Williams[SUP]2[/SUP] , J Yimmy Chow[SUP]2[/SUP] , Felicity Aiano[SUP]1[/SUP] , Katja Hoschler[SUP]1[/SUP] , Angie Lackenby[SUP]1[/SUP] , Joanna Ellis[SUP]1[/SUP] , Steven Platt[SUP]1[/SUP] , Shahjahan Miah[SUP]1[/SUP] , Kevin Brown[SUP]1[/SUP] , Gayatri Amirthalingam[SUP]1[/SUP] , Monika Patel[SUP]1[/SUP] , Mary E Ramsay[SUP]1[/SUP] , Robin Gopal[SUP]1[/SUP] , Andre Charlett[SUP]3[/SUP] , Shamez N Ladhani[SUP]1[/SUP] , Maria Zambon[SUP]1 [/SUP]

Two London care homes experienced a second COVID-19 outbreak, with 29/209 (13.9%) SARS-CoV-2 RT-PCR-positive cases (16/103 residents, 13/106 staff). In those with prior SARS-CoV-2 exposure, 1/88 (1.1%) individuals (antibody positive: 87; RT-PCR-positive: 1) became PCR-positive compared with 22/73 (30.1%) with confirmed seronegative status. After four months protection offered by prior infection against re-infection was 96.2% (95% confidence interval (CI): 72.7–99.5%) using risk ratios from comparison of proportions and 96.1% (95% CI: 78.8–99.3%) using a penalised logistic regression model.

full article

https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2021.26.5.2100092#abstract_content