tetano
Editor, Senior Moderator
An autochthonous case of Zika due to possible sexual transmission, Florence, Italy, 2014
G Venturi [SUP]1[/SUP] , L Zammarchi [SUP]2[/SUP] [SUP]3[/SUP] , C Fortuna [SUP]1[/SUP] , ME Remoli [SUP]1[/SUP] , E Benedetti [SUP]1[/SUP] , C Fiorentini [SUP]1[/SUP] , M Trotta [SUP]3[/SUP] , C Rizzo [SUP]4[/SUP] , A Mantella [SUP]2[/SUP] , G Rezza [SUP]1[/SUP] , A Bartoloni [SUP]2[/SUP] [SUP]3[/SUP]
+ Author affiliations
1. Department of Infectious, Parasitic and Immune-Mediate Diseases, Istituto Superiore di Sanit?, Rome, Italy
2. Clinica Malattie Infettive, Dipartimento di Medicina Sperimentale e Clinica, Universit? degli Studi di Firenze, Florence, Italy
3. SOD Malattie Infettive e Tropicali, Azienda Ospedaliero-Universitaria Caeggi, Florence, Italy
4. National Center for Epidemiology and Health Promotion, Istituto Superiore di Sanit?, Rome, Italy.
Correspondence: Alessandro Bartoloni (alessandro.bartoloni@unifi.it)
Citation style for this article: Venturi G, Zammarchi L, Fortuna C, Remoli M, Benedetti E, Fiorentini C, Trotta M, Rizzo C, Mantella A, Rezza G, Bartoloni A. An autochthonous case of Zika due to possible sexual transmission, Florence, Italy, 2014. Euro Surveill. 2016;21(8)
ii=30148. DOI: http://dx.doi.org/10.2807/1560-7917.ES.2016.21.8.30148
Received:16 February 2016; Accepted:25 February 2016
[h=4][/h]
We report a case of Zika virus infection imported in Florence, Italy ex-Thailand, leading to a secondary autochthonous case, probably through sexual transmission. The two cases occurred in May 2014 but were retrospectively diagnosed in 2016 on the basis of serological tests (plaque reduction neutralisation) performed on stored serum samples. Our report provides further evidence that sexual transmission of Zika virus is possible.
[h=2]Case reports[/h] At the beginning of May 2014, an Italian man is his early 30s (patient 1) returned to Florence, Italy, after a 10-day holiday in Thailand. On the day after his arrival, he developed a confluent maculopapular rash, on the face, trunk, arms, and legs, with fever (maximum temperature 38 ?C), conjunctivitis, and frontal headache with retroocular pain.
Four days later, patient 1 was admitted to the Infectious and Tropical Diseases Unit of the Florence Careggi University Hospital. Blood tests revealed leucopenia (3,000 cells/?L; reference: 4,000?10,000/?L) while creatinine, platelet count and transaminases were normal. Serological investigation two days after (i.e. 6 days after symptoms onset), showed past exposure to measles and parvovirus, negative results for human immunodeficiency virus (HIV) 1?2 Ab/Ag and chikungunya IgM, a positive result for dengue virus (DENV) IgM, and negative results for DENV IgG, as well as DENV NS1 Ag (Table).
...
http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=21395
G Venturi [SUP]1[/SUP] , L Zammarchi [SUP]2[/SUP] [SUP]3[/SUP] , C Fortuna [SUP]1[/SUP] , ME Remoli [SUP]1[/SUP] , E Benedetti [SUP]1[/SUP] , C Fiorentini [SUP]1[/SUP] , M Trotta [SUP]3[/SUP] , C Rizzo [SUP]4[/SUP] , A Mantella [SUP]2[/SUP] , G Rezza [SUP]1[/SUP] , A Bartoloni [SUP]2[/SUP] [SUP]3[/SUP]
+ Author affiliations
1. Department of Infectious, Parasitic and Immune-Mediate Diseases, Istituto Superiore di Sanit?, Rome, Italy
2. Clinica Malattie Infettive, Dipartimento di Medicina Sperimentale e Clinica, Universit? degli Studi di Firenze, Florence, Italy
3. SOD Malattie Infettive e Tropicali, Azienda Ospedaliero-Universitaria Caeggi, Florence, Italy
4. National Center for Epidemiology and Health Promotion, Istituto Superiore di Sanit?, Rome, Italy.
Correspondence: Alessandro Bartoloni (alessandro.bartoloni@unifi.it)
Citation style for this article: Venturi G, Zammarchi L, Fortuna C, Remoli M, Benedetti E, Fiorentini C, Trotta M, Rizzo C, Mantella A, Rezza G, Bartoloni A. An autochthonous case of Zika due to possible sexual transmission, Florence, Italy, 2014. Euro Surveill. 2016;21(8)
ii=30148. DOI: http://dx.doi.org/10.2807/1560-7917.ES.2016.21.8.30148Received:16 February 2016; Accepted:25 February 2016
[h=4][/h]
We report a case of Zika virus infection imported in Florence, Italy ex-Thailand, leading to a secondary autochthonous case, probably through sexual transmission. The two cases occurred in May 2014 but were retrospectively diagnosed in 2016 on the basis of serological tests (plaque reduction neutralisation) performed on stored serum samples. Our report provides further evidence that sexual transmission of Zika virus is possible.
[h=2]Case reports[/h] At the beginning of May 2014, an Italian man is his early 30s (patient 1) returned to Florence, Italy, after a 10-day holiday in Thailand. On the day after his arrival, he developed a confluent maculopapular rash, on the face, trunk, arms, and legs, with fever (maximum temperature 38 ?C), conjunctivitis, and frontal headache with retroocular pain.
Four days later, patient 1 was admitted to the Infectious and Tropical Diseases Unit of the Florence Careggi University Hospital. Blood tests revealed leucopenia (3,000 cells/?L; reference: 4,000?10,000/?L) while creatinine, platelet count and transaminases were normal. Serological investigation two days after (i.e. 6 days after symptoms onset), showed past exposure to measles and parvovirus, negative results for human immunodeficiency virus (HIV) 1?2 Ab/Ag and chikungunya IgM, a positive result for dengue virus (DENV) IgM, and negative results for DENV IgG, as well as DENV NS1 Ag (Table).
...
http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=21395