Euro Surveill. Treatment failure of pharyngeal gonorrhoea with internationally recommended first-line ceftriaxone verified in Slovenia, September 2011

[Giuseppe]

[Source: Eurosurveillance, full text: (LINK). Abstract, edited.]

Eurosurveillance, Volume 17, Issue 25, 21 June 2012

Rapid communications

Treatment failure of pharyngeal gonorrhoea with internationally recommended first-line ceftriaxone verified in Slovenia, September 2011

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M Unemo ()<SUP>1</SUP>, D Golparian<SUP>1</SUP>, M Potočnik<SUP>2</SUP>, S Jeverica<SUP>3</SUP>

1. World Health Organization Collaborating Centre for Gonorrhoea and other Sexually Transmitted Infections, Swedish Reference Laboratory for Pathogenic Neisseria, Department of Laboratory Medicine, Microbiology, ?rebro University Hospital, ?rebro, Sweden
2. Department of Dermatovenereology, University Medical Centre Ljubljana, Ljubljana, Slovenia
3. Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

<HR>
Citation style for this article: Unemo M, Golparian D, Potočnik M, Jeverica S. Treatment failure of pharyngeal gonorrhoea with internationally recommended first-line ceftriaxone verified in Slovenia, September 2011. Euro Surveill. 2012;17(25)ii=20200. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20200
Date of submission: 13 June 2012 <HR>We describe the second case in Europe of verified treatment failure of pharyngeal gonorrhoea, caused by an internationally occurring multidrug-resistant gonococcal clone, with recommended first-line ceftriaxone 250 mg in Slovenia. This is of grave concern since ceftriaxone is last remaining option for empirical treatment. Increased awareness of ceftriaxone failures, more frequent test-of-cure, strict adherence to regularly updated treatment guidelines, and thorough verification/falsification of suspected treatment failures are essential globally. New effective treatment options are imperative.
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