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Euro Surveill. Early estimates of influenza vaccine effectiveness in Navarre, Spain: 2012/13 mid-season analysis

Giuseppe

Emeritus
[Source: Eurosurveillance, full text: (LINK). Abstract, edited.]

Eurosurveillance, Volume 18, Issue 7, 14 February 2013

Rapid communications

Early estimates of influenza vaccine effectiveness in Navarre, Spain: 2012/13 mid-season analysis


J Castilla ()<SUP>1</SUP><SUP>,2</SUP>, I Mart?nez-Baz<SUP>1</SUP><SUP>,2</SUP>, V Mart?nez-Artola<SUP>3</SUP>, M Fernandez-Alonso<SUP>4</SUP>, G Reina<SUP>4</SUP>, M Guevara<SUP>1</SUP><SUP>,2</SUP>, M Garc?a Cenoz<SUP>1</SUP><SUP>,2</SUP>, F El?a<SUP>5</SUP>, N Alvarez<SUP>6</SUP>
  1. Instituto de Salud P?blica de Navarra (Public Health Institute of Navarre), Pamplona, Spain
  2. Centro de Investigaci?n Biom?dica en Red de Epidemiolog?a y Salud P?blica (CIBERESP; Network of Biomedical Research Centers Epidemiology and Public Health), Spain
  3. Complejo Hospitalario de Navarra (Hospital Complex of Navarre), Pamplona, Spain
  4. Cl?nica Universidad de Navarra (University Clinic of Navarre), Pamplona, Spain
  5. Primary Healthcare Directorate, Navarre Health Service, Pamplona, Spain
  6. Servicio Navarro de Salud (Navarre Health Service), Pamplona, Spain
<HR>
Citation style for this article: Castilla J, Mart?nez-Baz I, Mart?nez-Artola V, Fernandez-Alonso M, Reina G, Guevara M, Garc?a Cenoz M, El?a F, Alvarez N. Early estimates of influenza vaccine effectiveness in Navarre, Spain: 2012/13 mid-season analysis. Euro Surveill. 2013;18(7):pii=20404. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20404
Date of submission: 01 February 2013
<HR>We present estimates of influenza vaccine effectiveness (VE) in Navarre, Spain, in the early 2012/13 season, which was dominated by influenza B. In a population-based cohort using electronic records from physicians, the adjusted VE in preventing influenza-like illness was 32% (95% confidence interval (CI): 15 to 46). In a nested test-negative case?control analysis the adjusted VE in preventing laboratory-confirmed influenza was 86% (95% CI: 45 to 96). These results suggest a high protective effect of the vaccine.
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