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Euro Surveill. Assessing the risk of a community outbreak of hepatitis A on blood safety in Latvia, 2008

Giuseppe

Emeritus
Assessing the risk of a community outbreak of hepatitis A on blood safety in Latvia, 2008 (Euro Surveill., abstract, edited)


[Source: EuroSurveillance.og, full text and abstract: <cite cite="http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19640">Eurosurveillance - View Article</cite>. Edited.]

Eurosurveillance, Volume 15, Issue 33, 19 August 2010
Research articles

Assessing the risk of a community outbreak of hepatitis A on blood safety in Latvia, 2008

J Perevo?čikovs 1, A Lenglet 2, I Lucenko 1, A ?teinerte 3, L Payne Hallstr?m 2, D Coulombier 2
1. Latvian State Public Health Agency, Riga, Latvia
2. Preparedness and Response Support Unit, European Centre for Disease Prevention and Control, Stockholm, Sweden
3. State Blood Donor Centre, Riga, Latvia

Citation style for this article: Perevo?čikovs J, Lenglet A, Lucenko I, ?teinerte A, Payne Hallstr?m L, Coulombier D. Assessing the risk of a community outbreak of hepatitis A on blood safety in Latvia, 2008. Euro Surveill. 2010;15(33):pii=19640. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19640

Date of submission: 06 April 2010


Post-transfusion hepatitis A virus (HAV) infection worldwide is considered a sporadic event. An outbreak of HAV infection occurred in Latvia between the end of 2007 and throughout 2008 with more than 2,800 confirmed cases reported over a 13-month period (incidence of 123 per 100,000 population). The majority of reported HAV infection cases were in people over 18 years of age and in people living in the capital city, Riga. We estimated that the crude risk for HAV contamination of whole blood supplies in Riga between February and October 2008 ranged from 1.4 to 10.6per 10,000 donated units. In people under 40 years of age, the risk of receiving an infectious blood transfusion was more than 3.0 per 10,000 recipients between August and October 2008 during the peak of the outbreak. We conclude that there is a previously under-recognised impact of HAV on blood safety during widespread outbreaks of this disease. Estimating the risk of contamination of blood supplies during an infectious disease outbreak scenario is important for fine tuning risk assessments and potentially improving public health practices.

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