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Editor, Senior Moderator
Eur Radiol. 2020 May 12. doi: 10.1007/s00330-020-06928-0. [Epub ahead of print]
COVID-19 pneumonia: CT findings of 122 patients and differentiation from influenza pneumonia.
Liu M[SUP]1[/SUP], Zeng W[SUP]2[/SUP], Wen Y[SUP]2[/SUP], Zheng Y[SUP]1[/SUP], Lv F[SUP]3[/SUP], Xiao K[SUP]4[/SUP].
Author information
Abstract
OBJECTIVES:
To investigate the clinical and chest CT characteristics of COVID-19 pneumonia and explore the radiological differences between COVID-19 and influenza.
MATERIALS AND METHODS:
A total of 122 patients (61 men and 61 women, 48 ? 15 years) confirmed with COVID-19 and 48 patients (23 men and 25 women, 47 ? 19 years) confirmed with influenza were enrolled in the study. Thin-section CT was performed. The clinical data and the chest CT findings were recorded.
RESULTS:
The most common symptoms of COVID-19 were fever (74%) and cough (63%), and 102 patients (83%) had Wuhan contact. Pneumonia in 50 patients with COVID-19 (45%) distributed in the peripheral regions of the lung, while it showed mixed distribution in 26 patients (74%) with influenza (p = 0.022). The most common CT features of the COVID-19 group were pure ground-glass opacities (GGO, 36%), GGO with consolidation (51%), rounded opacities (35%), linear opacities (64%), bronchiolar wall thickening (49%), and interlobular septal thickening (66%). Compared with the influenza group, the COVID-19 group was more likely to have rounded opacities (35% vs. 17%, p = 0.048) and interlobular septal thickening (66% vs. 43%, p = 0.014), but less likely to have nodules (28% vs. 71%, p < 0.001), tree-in-bud sign (9% vs. 40%, p < 0.001), and pleural effusion (6% vs. 31%, p < 0.001).
CONCLUSIONS:
There are significant differences in the CT manifestations of patients with COVID-19 and influenza. Presence of rounded opacities and interlobular septal thickening, with the absence of nodules and tree-in-bud sign, and with the typical peripheral distribution, may help us differentiate COVID-19 from influenza.
KEY POINTS:
• Typical CT features of COVID-19 include pure ground-glass opacities (GGO), GGO with consolidation, rounded opacities, bronchiolar wall thickening, interlobular septal thickening, and a peripheral distribution. • Presence of rounded opacities and interlobular septal thickening, with the absence of nodules and tree-in-bud sign, and with the typical peripheral distribution, may help us differentiate COVID-19 from influenza.
KEYWORDS:
Coronavirus infections; Human; Influenza; Pneumonia, viral; Tomography, x-ray computed
PMID:32399710DOI:10.1007/s00330-020-06928-0
Free PMC Article
COVID-19 pneumonia: CT findings of 122 patients and differentiation from influenza pneumonia.
Liu M[SUP]1[/SUP], Zeng W[SUP]2[/SUP], Wen Y[SUP]2[/SUP], Zheng Y[SUP]1[/SUP], Lv F[SUP]3[/SUP], Xiao K[SUP]4[/SUP].
Author information
Abstract
OBJECTIVES:
To investigate the clinical and chest CT characteristics of COVID-19 pneumonia and explore the radiological differences between COVID-19 and influenza.
MATERIALS AND METHODS:
A total of 122 patients (61 men and 61 women, 48 ? 15 years) confirmed with COVID-19 and 48 patients (23 men and 25 women, 47 ? 19 years) confirmed with influenza were enrolled in the study. Thin-section CT was performed. The clinical data and the chest CT findings were recorded.
RESULTS:
The most common symptoms of COVID-19 were fever (74%) and cough (63%), and 102 patients (83%) had Wuhan contact. Pneumonia in 50 patients with COVID-19 (45%) distributed in the peripheral regions of the lung, while it showed mixed distribution in 26 patients (74%) with influenza (p = 0.022). The most common CT features of the COVID-19 group were pure ground-glass opacities (GGO, 36%), GGO with consolidation (51%), rounded opacities (35%), linear opacities (64%), bronchiolar wall thickening (49%), and interlobular septal thickening (66%). Compared with the influenza group, the COVID-19 group was more likely to have rounded opacities (35% vs. 17%, p = 0.048) and interlobular septal thickening (66% vs. 43%, p = 0.014), but less likely to have nodules (28% vs. 71%, p < 0.001), tree-in-bud sign (9% vs. 40%, p < 0.001), and pleural effusion (6% vs. 31%, p < 0.001).
CONCLUSIONS:
There are significant differences in the CT manifestations of patients with COVID-19 and influenza. Presence of rounded opacities and interlobular septal thickening, with the absence of nodules and tree-in-bud sign, and with the typical peripheral distribution, may help us differentiate COVID-19 from influenza.
KEY POINTS:
• Typical CT features of COVID-19 include pure ground-glass opacities (GGO), GGO with consolidation, rounded opacities, bronchiolar wall thickening, interlobular septal thickening, and a peripheral distribution. • Presence of rounded opacities and interlobular septal thickening, with the absence of nodules and tree-in-bud sign, and with the typical peripheral distribution, may help us differentiate COVID-19 from influenza.
KEYWORDS:
Coronavirus infections; Human; Influenza; Pneumonia, viral; Tomography, x-ray computed
PMID:32399710DOI:10.1007/s00330-020-06928-0
Free PMC Article