Giuseppe
Emeritus
Estimating influenza-related excess mortality and reproduction numbers for seasonal influenza in Norway, 1975-2004. (Epidemiol Infect., abstract, edited)
[Source: US National Library of Medicine, (LINK). Edited.]
Epidemiol Infect. 2010 Mar 25:1-10. [Epub ahead of print]
Estimating influenza-related excess mortality and reproduction numbers for seasonal influenza in Norway, 1975-2004.
Gran JM, Iversen B, Hungnes O, Aalen OO. - Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
SUMMARY
Influenza can be a serious, sometimes deadly, disease, especially for people in high-risk groups such as the elderly and patients with underlying, severe disease. In this paper we estimated the influenza-related excess mortality in Norway for 1975-2004, comparing it with dominant virus types and estimates of the reproduction number. Analysis was done using Poisson regression, explaining the weekly all-cause mortality by rates of reported influenza-like illness, together with markers for seasonal and year-to-year variation. The estimated excess mortality was the difference between the observed and predicted mortality, removing the influenza contribution from the prediction. We estimated the overall influenza-related excess mortality as 910 deaths per season, or 2.08% of the overall deaths. Age-grouped analyses indicated that the major part of the excess mortality occurred in the 65 years age group, but that there was also a significant contribution to mortality in the 0-4 years age group. Estimates of the reproduction number R, ranged from about 1 to 1.69.
PMID: 20334732 [PubMed - as supplied by publisher]
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[Source: US National Library of Medicine, (LINK). Edited.]
Epidemiol Infect. 2010 Mar 25:1-10. [Epub ahead of print]
Estimating influenza-related excess mortality and reproduction numbers for seasonal influenza in Norway, 1975-2004.
Gran JM, Iversen B, Hungnes O, Aalen OO. - Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
SUMMARY
Influenza can be a serious, sometimes deadly, disease, especially for people in high-risk groups such as the elderly and patients with underlying, severe disease. In this paper we estimated the influenza-related excess mortality in Norway for 1975-2004, comparing it with dominant virus types and estimates of the reproduction number. Analysis was done using Poisson regression, explaining the weekly all-cause mortality by rates of reported influenza-like illness, together with markers for seasonal and year-to-year variation. The estimated excess mortality was the difference between the observed and predicted mortality, removing the influenza contribution from the prediction. We estimated the overall influenza-related excess mortality as 910 deaths per season, or 2.08% of the overall deaths. Age-grouped analyses indicated that the major part of the excess mortality occurred in the 65 years age group, but that there was also a significant contribution to mortality in the 0-4 years age group. Estimates of the reproduction number R, ranged from about 1 to 1.69.
PMID: 20334732 [PubMed - as supplied by publisher]
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