tetano
Editor, Senior Moderator
J Clin Microbiol. 2014 Mar 5. [Epub ahead of print]
Emergence of G186D in the Presence of R292K in an Immunocompromised Child Infected with Influenza A/H3N2 Treated with Oseltamivir.
Lee HK1, Tang JW, Loh TP, Kong DH, Lau YW, Yap HK, Koay ES.
Author information
Abstract
An immunocompromised child with influenza A/H3N2 infection, treated with oseltamivir from day 1, had nasal swabs taken on days 1, 4, 7 and 10 of illness. Pyrosequencing showed increasing proportions of viruses with R292K (neuraminidase gene) and G186D (hemagglutinin gene) mutations, resulting in a viral load rebound by day 10.
PMID:
24599981
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24599981
Emergence of G186D in the Presence of R292K in an Immunocompromised Child Infected with Influenza A/H3N2 Treated with Oseltamivir.
Lee HK1, Tang JW, Loh TP, Kong DH, Lau YW, Yap HK, Koay ES.
Author information
Abstract
An immunocompromised child with influenza A/H3N2 infection, treated with oseltamivir from day 1, had nasal swabs taken on days 1, 4, 7 and 10 of illness. Pyrosequencing showed increasing proportions of viruses with R292K (neuraminidase gene) and G186D (hemagglutinin gene) mutations, resulting in a viral load rebound by day 10.
PMID:
24599981
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24599981