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Emergence of an Autochthonous and Community-Acquired NDM-1?Producing Klebsiella pneumoniae in Europe

Gert van der Hoek

In Memoriam - Editor, Senior Moderator
Emergence of an Autochthonous and Community-Acquired NDM-1–Producing Klebsiella pneumoniae in Europe

TO THE EDITOR—The recently identitified carbapenemase New Dehli metallo-β-lactamase (NDM-1) inactivates all β-lactams except aztreonam [ 1]. The corresponding gene that is usually plasmid-borne has spread mostly in Escherichia coli and Klebsiella pneumoniae [ 1, 2]. NDM-1 producers are multidrug resistant or even resistant to all antibiotics [ 1, 2]. Whereas contamination with NDM-1 producers is mostly hospital associated, rare cases of community acquisition are known and have been traced to the Indian subcontinent [ 2].

Here, we report a woman aged 83 years who had cystitis due to a multidrug-resistant K. pneumoniae in June 2011. She had a history of multiple and recurrent episodes of urinary tract infections caused by diverse Enterobacteriaceae that were always treated with …

read more behind a paywall........ ; no abstract available yet. Taxpayers often are not allowed to read the results of research they paid for ....

Clin Infect Dis. 2011 Sep 29.
 
Re: Emergence of an Autochthonous and Community-Acquired NDM-1?Producing Klebsiella pneumoniae in Europe

Emergence of an Autochthonous and Community-Acquired NDM-1–Producing Klebsiella pneumoniae in Europe

TO THE EDITOR—The recently identitified carbapenemase New Dehli metallo-β-lactamase (NDM-1) inactivates all β-lactams except aztreonam [ 1]. The corresponding gene that is usually plasmid-borne has spread mostly in Escherichia coli and Klebsiella pneumoniae [ 1, 2]. NDM-1 producers are multidrug resistant or even resistant to all antibiotics [ 1, 2]. Whereas contamination with NDM-1 producers is mostly hospital associated, rare cases of community acquisition are known and have been traced to the Indian subcontinent [ 2].

Here, we report a woman aged 83 years who had cystitis due to a multidrug-resistant K. pneumoniae in June 2011. She had a history of multiple and recurrent episodes of urinary tract infections caused by diverse Enterobacteriaceae that were always treated with …

read more behind a paywall........ ; no abstract available yet. Taxpayers often are not allowed to read the results of research they paid for ....

Clin Infect Dis. 2011 Sep 29.

It is very disturbing that we can not see even an abstract for this paper about an emerging world wide health threat. Not humanitarian. :(

Panama - 81 people have died as a result of the bacterium Klebsiella pneumoniae carbapenemase (KPC) resistant
 
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