Giuseppe
Emeritus
Swine Influenza A Vaccines, Pandemic (H1N1) 2009 Virus, and Cross-Reactivity (Emerg Infect Dis., extract, edited)
[Source: Emerging Infectious Diseases Journal, Full PDF Document (LINK). Extract, edited.]
DOI: 10.3201/eid1606.100138
Suggested citation for this article: D?rrwald R, Krumbholz A, Baumgarte S, Schlegel M, Vahlenkamp TW, Selbitz H-J, et al. Swine influenza A vaccines, pandemic (H1N1) 2009 virus, and cross-reactivity [letter]. Emerg Infect Dis. 2010 Jun; [Epub ahead of print]
Swine Influenza A Vaccines, Pandemic (H1N1) 2009 Virus, and Cross-Reactivity
To the Editor:
Since its first emergence in the human population in spring 2009 (1?3) infections with pandemic (H1N1) 2009 virus have been reported in pigs, turkeys, and some carnivore species (4,5). The pandemic (H1N1) 2009 virus can be experimentally transmitted between pigs (6). The reported transmissibility of the virus raises the question as to whether authorized swine influenza vaccine strains may be cross-reactive to pandemic (H1N1) 2009 virus. Kyriakis et al. (7) investigated the cross-reactivity of 66 pig serum samples from different infection and vaccination trials and reported cross-reactions between the avian-like H1N1 viruses circulating in the European pig population (avH1N1) and the classical swine H1N1 viruses (cH1N1) with pandemic (H1N1) 2009 virus by hemagglutination inhibition assay.
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[Source: Emerging Infectious Diseases Journal, Full PDF Document (LINK). Extract, edited.]
DOI: 10.3201/eid1606.100138
Suggested citation for this article: D?rrwald R, Krumbholz A, Baumgarte S, Schlegel M, Vahlenkamp TW, Selbitz H-J, et al. Swine influenza A vaccines, pandemic (H1N1) 2009 virus, and cross-reactivity [letter]. Emerg Infect Dis. 2010 Jun; [Epub ahead of print]
Swine Influenza A Vaccines, Pandemic (H1N1) 2009 Virus, and Cross-Reactivity
To the Editor:
Since its first emergence in the human population in spring 2009 (1?3) infections with pandemic (H1N1) 2009 virus have been reported in pigs, turkeys, and some carnivore species (4,5). The pandemic (H1N1) 2009 virus can be experimentally transmitted between pigs (6). The reported transmissibility of the virus raises the question as to whether authorized swine influenza vaccine strains may be cross-reactive to pandemic (H1N1) 2009 virus. Kyriakis et al. (7) investigated the cross-reactivity of 66 pig serum samples from different infection and vaccination trials and reported cross-reactions between the avian-like H1N1 viruses circulating in the European pig population (avH1N1) and the classical swine H1N1 viruses (cH1N1) with pandemic (H1N1) 2009 virus by hemagglutination inhibition assay.
(...)
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