tetano
Editor, Senior Moderator
Emerg Infect Dis
. 2022 May 12;28(7).
doi: 10.3201/eid2807.220526. Online ahead of print.
SARS-CoV-2 Delta-Omicron Recombinant Viruses, United States
Kristine A Lacek, Benjamin L Rambo-Martin, Dhwani Batra, Xiao-Yu Zheng, Norman Hassell, Hitoshi Sakaguchi, Thomas Peacock, Natalie Groves, Matthew Keller, Malania M Wilson, Mili Sheth, Morgan L Davis, Mark Borroughs, Jonathan Gerhart, Samuel S Shepard, Peter W Cook, Justin Lee, David E Wentworth, John R Barnes, Rebecca Kondor, Clinton R Paden
Abstract
To detect new and changing SARS-CoV-2 variants, we investigated candidate Delta-Omicron recombinant genomes from Centers for Disease Control and Prevention national genomic surveillance. Laboratory and bioinformatic investigations identified and validated 9 genetically related SARS-CoV-2 viruses with a hybrid Delta-Omicron spike protein.
Keywords: 2019 novel coronavirus disease; COVID-19; Delta; Omicron; SARS-CoV-2; United States; bioinformatics; coronavirus disease; next-generation sequencing; recombination; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.
. 2022 May 12;28(7).
doi: 10.3201/eid2807.220526. Online ahead of print.
SARS-CoV-2 Delta-Omicron Recombinant Viruses, United States
Kristine A Lacek, Benjamin L Rambo-Martin, Dhwani Batra, Xiao-Yu Zheng, Norman Hassell, Hitoshi Sakaguchi, Thomas Peacock, Natalie Groves, Matthew Keller, Malania M Wilson, Mili Sheth, Morgan L Davis, Mark Borroughs, Jonathan Gerhart, Samuel S Shepard, Peter W Cook, Justin Lee, David E Wentworth, John R Barnes, Rebecca Kondor, Clinton R Paden
- PMID: 35551714
- DOI: 10.3201/eid2807.220526
Abstract
To detect new and changing SARS-CoV-2 variants, we investigated candidate Delta-Omicron recombinant genomes from Centers for Disease Control and Prevention national genomic surveillance. Laboratory and bioinformatic investigations identified and validated 9 genetically related SARS-CoV-2 viruses with a hybrid Delta-Omicron spike protein.
Keywords: 2019 novel coronavirus disease; COVID-19; Delta; Omicron; SARS-CoV-2; United States; bioinformatics; coronavirus disease; next-generation sequencing; recombination; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.