tetano
Editor, Senior Moderator
Emerg Infect Dis
. 2024 Nov;30(11):2362-2369.
doi: 10.3201/eid3011.240375.
Estimating Influenza Illnesses Averted by Year-Round and Seasonal Campaign Vaccination for Young Children, Kenya
Radhika Gharpure, Young M Yoo, Ben Andagalu, Stefano Tempia, Sergio Loayza, Chiedza Machingaidze, Bryan O Nyawanda, Jeanette Dawa, Eric Osoro, Rose Jalang'o, Kathryn E Lafond, Melissa A Rolfes, Gideon O Emukule
In Kenya, influenza virus circulates year-round, raising questions about optimum strategies for vaccination. Given national interest in introducing influenza vaccination for young children 6-23 months of age, we modeled total influenza-associated illnesses (inclusive of hospitalizations, outpatient illnesses, and non‒medically attended illnesses) averted by multiple potential vaccination strategies: year-round versus seasonal-campaign vaccination, and vaccination starting in April (Southern Hemisphere influenza vaccine availability) versus October (Northern Hemisphere availability). We modeled average vaccine effectiveness of 50% and annual vaccination coverage of 60%. In the introduction year, year-round vaccination averted 6,410 total illnesses when introduced in October and 7,202 illnesses when introduced in April, whereas seasonal-campaign vaccination averted 10,236 (October) to 11,612 (April) illnesses. In the year after introduction, both strategies averted comparable numbers of illnesses (10,831-10,868 for year-round, 10,175-11,282 for campaign). Campaign-style vaccination would likely have a greater effect during initial pediatric influenza vaccine introduction in Kenya; however, either strategy could achieve similar longer-term effects.
Keywords: Kenya; child; influenza; respiratory infections; vaccination; vaccines; viruses.
. 2024 Nov;30(11):2362-2369.
doi: 10.3201/eid3011.240375.
Estimating Influenza Illnesses Averted by Year-Round and Seasonal Campaign Vaccination for Young Children, Kenya
Radhika Gharpure, Young M Yoo, Ben Andagalu, Stefano Tempia, Sergio Loayza, Chiedza Machingaidze, Bryan O Nyawanda, Jeanette Dawa, Eric Osoro, Rose Jalang'o, Kathryn E Lafond, Melissa A Rolfes, Gideon O Emukule
- PMID: 39447183
- DOI: 10.3201/eid3011.240375
In Kenya, influenza virus circulates year-round, raising questions about optimum strategies for vaccination. Given national interest in introducing influenza vaccination for young children 6-23 months of age, we modeled total influenza-associated illnesses (inclusive of hospitalizations, outpatient illnesses, and non‒medically attended illnesses) averted by multiple potential vaccination strategies: year-round versus seasonal-campaign vaccination, and vaccination starting in April (Southern Hemisphere influenza vaccine availability) versus October (Northern Hemisphere availability). We modeled average vaccine effectiveness of 50% and annual vaccination coverage of 60%. In the introduction year, year-round vaccination averted 6,410 total illnesses when introduced in October and 7,202 illnesses when introduced in April, whereas seasonal-campaign vaccination averted 10,236 (October) to 11,612 (April) illnesses. In the year after introduction, both strategies averted comparable numbers of illnesses (10,831-10,868 for year-round, 10,175-11,282 for campaign). Campaign-style vaccination would likely have a greater effect during initial pediatric influenza vaccine introduction in Kenya; however, either strategy could achieve similar longer-term effects.
Keywords: Kenya; child; influenza; respiratory infections; vaccination; vaccines; viruses.