Giuseppe
Emeritus
[Source: US Centers for Disease Control and Prevention (CDC), Emerging Infectious Diseases Journal, full page: (LINK). Abstract, edited.]
Volume 20, Number 1?January 2014 / Dispatch
Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease
Jean Yves Douet, Saima Zafar, Armand Perret-Liaudet, Caroline Lacroux, S?verine Lugan, Naima Aron, Herve Cassard, Claudia Ponto, Fabien Corbi?re, Juan Maria Torres, Inga Zerr, and Olivier Andreoletti
Author affiliations: Ecole Nationale V?t?rinaire Toulouse, France (J.Y. Douet, C. Lacroux, S. Lugan, N. Aron, H. Cassard, F. Corbi?re, O. Andr?oletti); National Reference Center for Transmissible Spongiform Encephalopathy, Georg August University, G?ttingen, Germany (S. Zafar, C. Ponto, I. Zerr); Hospices Civils de Lyon, France (A. Perret-Liaudet); BioRan, Bron, France (A. Perret-Liaudet); Centro de Investigaci?n en Sanidad Animal, Madrid, Spain (J.M. Torres)
Abstract
We report the presence of infectivity in erythrocytes, leukocytes, and plasma of 1 person with variant Creutzfeldt-Jakob disease and in the plasma of 2 in 4 persons whose tests were positive for sporadic Creutzfeldt-Jakob disease. The measured infectivity levels were comparable to those reported in various animals with transmissible spongiform encephalopathies.
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Volume 20, Number 1?January 2014 / Dispatch
Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease
Jean Yves Douet, Saima Zafar, Armand Perret-Liaudet, Caroline Lacroux, S?verine Lugan, Naima Aron, Herve Cassard, Claudia Ponto, Fabien Corbi?re, Juan Maria Torres, Inga Zerr, and Olivier Andreoletti
Author affiliations: Ecole Nationale V?t?rinaire Toulouse, France (J.Y. Douet, C. Lacroux, S. Lugan, N. Aron, H. Cassard, F. Corbi?re, O. Andr?oletti); National Reference Center for Transmissible Spongiform Encephalopathy, Georg August University, G?ttingen, Germany (S. Zafar, C. Ponto, I. Zerr); Hospices Civils de Lyon, France (A. Perret-Liaudet); BioRan, Bron, France (A. Perret-Liaudet); Centro de Investigaci?n en Sanidad Animal, Madrid, Spain (J.M. Torres)
Abstract
We report the presence of infectivity in erythrocytes, leukocytes, and plasma of 1 person with variant Creutzfeldt-Jakob disease and in the plasma of 2 in 4 persons whose tests were positive for sporadic Creutzfeldt-Jakob disease. The measured infectivity levels were comparable to those reported in various animals with transmissible spongiform encephalopathies.
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