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Emerg Infect Dis . Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan

tetano

Editor, Senior Moderator
Emerg Infect Dis


. 2020 Dec;26(12):3025-3029.
doi: 10.3201/eid2612.203386.
Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan

Shin Murakami, Tomoya Kitamura, Jin Suzuki, Ryouta Sato, Toshiki Aoi, Marina Fujii, Hiromichi Matsugo, Haruhiko Kamiki, Hiroho Ishida, Akiko Takenaka-Uema, Masayuki Shimojima, Taisuke Horimoto

Abstract

Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus' spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor.

Keywords: COVID-19; Japan; Rhinolophus cornutus; SARS; SARS-CoV-2; bat sarbecovirus; betacoronavirus; coronavirus; coronavirus disease; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.
 
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