tetano
Editor, Senior Moderator
Emerg Infect Dis
. 2023 Oct 26;29(12).
doi: 10.3201/eid2912.221916. Online ahead of print.
Anthropogenic Transmission of SARS-CoV-2 from Humans to Lions, Singapore, 2021
Yin Cheong Aden Ip, Adrian Tan, Jasmine Ong, Charlene Judith Fernandez, Clara Lau, Wai Kwan Wong, Siow Foong Chang, Him Hoo Yap, Kenneth B H Er
In Singapore, 10 captive lions tested positive for SARS-CoV-2 by real-time PCR. Genomic analyses of nanopore sequencing confirmed human-to-animal transmission of the SARS-CoV-2 Delta variant. Viral genomes from the lions and zookeeper shared a unique spike protein substitution, S:A1016V. Widespread SARS-CoV-2 transmission among humans can increase the likelihood of anthroponosis.
Keywords: COVID-19; Delta variant; Panthera; SARS-CoV-2; Singapore; coronavirus; endangered species; human-to-animal transmission; lion; nanopore sequencing; respiratory infections; reverse zoonosis; viral genome; viruses; zoo; zoonoses.
. 2023 Oct 26;29(12).
doi: 10.3201/eid2912.221916. Online ahead of print.
Anthropogenic Transmission of SARS-CoV-2 from Humans to Lions, Singapore, 2021
Yin Cheong Aden Ip, Adrian Tan, Jasmine Ong, Charlene Judith Fernandez, Clara Lau, Wai Kwan Wong, Siow Foong Chang, Him Hoo Yap, Kenneth B H Er
- PMID: 37885046
- DOI: 10.3201/eid2912.221916
In Singapore, 10 captive lions tested positive for SARS-CoV-2 by real-time PCR. Genomic analyses of nanopore sequencing confirmed human-to-animal transmission of the SARS-CoV-2 Delta variant. Viral genomes from the lions and zookeeper shared a unique spike protein substitution, S:A1016V. Widespread SARS-CoV-2 transmission among humans can increase the likelihood of anthroponosis.
Keywords: COVID-19; Delta variant; Panthera; SARS-CoV-2; Singapore; coronavirus; endangered species; human-to-animal transmission; lion; nanopore sequencing; respiratory infections; reverse zoonosis; viral genome; viruses; zoo; zoonoses.