Mary Wilson
Well-known member
JAMA. Published online March 25, 2021.
doi:10.1001/jama.2021.4682
Domenico Luca Grieco, MD[SUP]1,2[/SUP]; Luca S. Menga, MD[SUP]1,2[/SUP]; Melania Cesarano, MD[SUP]1,2[/SUP]; et al
Key Points
Question Among patients admitted to the intensive care unit with COVID-19?induced moderate to severe hypoxemic respiratory failure, does early continuous treatment with helmet noninvasive ventilation increase the number of days free of respiratory support at 28 days as compared with high-flow nasal oxygen?
Findings In this randomized trial that included 109 patients, the median number of days free of respiratory support within 28 days was 20 days in the group that received helmet noninvasive ventilation and 18 days in the group that received high-flow nasal oxygen, a difference that was not statistically significant.
Meaning Among critically ill patients with moderate to severe hypoxemic respiratory failure due to COVID-19, helmet noninvasive ventilation, compared with high-flow nasal oxygen, resulted in no significant difference in the number of days free of respiratory support within 28 days.
https://jamanetwork.com/journals/jama/fullarticle/2778088
doi:10.1001/jama.2021.4682
Domenico Luca Grieco, MD[SUP]1,2[/SUP]; Luca S. Menga, MD[SUP]1,2[/SUP]; Melania Cesarano, MD[SUP]1,2[/SUP]; et al
Key Points
Question Among patients admitted to the intensive care unit with COVID-19?induced moderate to severe hypoxemic respiratory failure, does early continuous treatment with helmet noninvasive ventilation increase the number of days free of respiratory support at 28 days as compared with high-flow nasal oxygen?
Findings In this randomized trial that included 109 patients, the median number of days free of respiratory support within 28 days was 20 days in the group that received helmet noninvasive ventilation and 18 days in the group that received high-flow nasal oxygen, a difference that was not statistically significant.
Meaning Among critically ill patients with moderate to severe hypoxemic respiratory failure due to COVID-19, helmet noninvasive ventilation, compared with high-flow nasal oxygen, resulted in no significant difference in the number of days free of respiratory support within 28 days.
https://jamanetwork.com/journals/jama/fullarticle/2778088