tetano
Editor, Senior Moderator
Epidemiol Infect. 2016 Aug 1:1-4. [Epub ahead of print]
[h=1]Did exposure to a severe outbreak of pandemic influenza in 1918 impact on long-term survival?[/h] Wilson N[SUP]1[/SUP], Boyd M[SUP]2[/SUP], Nisa S[SUP]3[/SUP], Clement C[SUP]4[/SUP], Baker MG[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] There is some suggestion that infection with pandemic influenza may increase long-term mortality risks. Therefore we aimed to determine if exposure to a severe outbreak of pandemic influenza on a troopship in 1918 impacted on lifespan in the survivors. The troopship with the outbreak cohort had 1107 personnel and the comparison cohort was from two contemporaneous troopships (1108 randomly selected personnel). Data were collected from online individual military files. The main finding was that there was no statistically significant difference in the lifespan of the outbreak cohort and the comparison cohort (means of 71?5 and 71?0 years, respectively). Indeed, the outbreak cohort was actually more likely to survive into the period from 1950 onwards (P = 0?036) and to participate in the Second World War (P = 0?043). There were no significant differences between the cohorts in terms of occupational class, but the comparison cohort had a higher proportion of rural occupations (33?3% vs. 27?0%, P < 0?001) and was very slightly older in mid-1918 (27?8 vs. 27?2 years, P = 0?028). In conclusion, this study found no support for the hypothesis that exposure to the 1918 influenza pandemic adversely impacted on the lifespan in the survivors, at least in this male and military-age population.
[h=4]KEYWORDS:[/h] Influenza; pandemic; public health emerging infections
PMID: 27477637 DOI: 10.1017/S0950268816001606
[PubMed - as supplied by publisher]
[h=1]Did exposure to a severe outbreak of pandemic influenza in 1918 impact on long-term survival?[/h] Wilson N[SUP]1[/SUP], Boyd M[SUP]2[/SUP], Nisa S[SUP]3[/SUP], Clement C[SUP]4[/SUP], Baker MG[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] There is some suggestion that infection with pandemic influenza may increase long-term mortality risks. Therefore we aimed to determine if exposure to a severe outbreak of pandemic influenza on a troopship in 1918 impacted on lifespan in the survivors. The troopship with the outbreak cohort had 1107 personnel and the comparison cohort was from two contemporaneous troopships (1108 randomly selected personnel). Data were collected from online individual military files. The main finding was that there was no statistically significant difference in the lifespan of the outbreak cohort and the comparison cohort (means of 71?5 and 71?0 years, respectively). Indeed, the outbreak cohort was actually more likely to survive into the period from 1950 onwards (P = 0?036) and to participate in the Second World War (P = 0?043). There were no significant differences between the cohorts in terms of occupational class, but the comparison cohort had a higher proportion of rural occupations (33?3% vs. 27?0%, P < 0?001) and was very slightly older in mid-1918 (27?8 vs. 27?2 years, P = 0?028). In conclusion, this study found no support for the hypothesis that exposure to the 1918 influenza pandemic adversely impacted on the lifespan in the survivors, at least in this male and military-age population.
[h=4]KEYWORDS:[/h] Influenza; pandemic; public health emerging infections
PMID: 27477637 DOI: 10.1017/S0950268816001606
[PubMed - as supplied by publisher]