sharon sanders
Editor-in-Chief & President
Testing of Diagnostic Methods for Detection of Influenza Virus for Optimal Performance in the Context of an Influenza Surveillance Network<SUP>
</SUP>
Mercedes P?rez-Ruiz,<SUP>1</SUP><SUP>*</SUP> Ruth Yeste,<SUP>1</SUP> Mar?a-Jos? Ruiz-P?rez,<SUP>1</SUP> Alfonso Ruiz-Bravo,<SUP>2</SUP> Manuel de la Rosa-Fraile,<SUP>1</SUP> and Jos? Mar?a Navarro-Mar?<SUP>1</SUP>
Servicio de Microbiolog?a, Hospital Universitario Virgen de las Nieves, Granada, Spain,<SUP>1</SUP> Departamento de Microbiolog?a, Universidad de Granada, Granada, Spain<SUP>2</SUP>
Received 30 March 2007/ Returned for modification 26 April 2007/ Accepted 16 July 2007 <!-- ABS -->Influenza surveillance networks must detect early the viruses<SUP> </SUP>that will cause the forthcoming annual epidemics and isolate<SUP> </SUP>the strains for further characterization. We obtained the highest<SUP> </SUP>sensitivity (95.4%) with a diagnostic tool that combined a shell-vial<SUP> </SUP>assay and reverse transcription-PCR on cell culture supernatants<SUP> </SUP>at 48 h, and indeed, recovered the strain.<SUP> </SUP>
<SUP></SUP>
http://jcm.asm.org/cgi/content/abstract/45/9/3109
Mercedes P?rez-Ruiz,<SUP>1</SUP><SUP>*</SUP> Ruth Yeste,<SUP>1</SUP> Mar?a-Jos? Ruiz-P?rez,<SUP>1</SUP> Alfonso Ruiz-Bravo,<SUP>2</SUP> Manuel de la Rosa-Fraile,<SUP>1</SUP> and Jos? Mar?a Navarro-Mar?<SUP>1</SUP>
Servicio de Microbiolog?a, Hospital Universitario Virgen de las Nieves, Granada, Spain,<SUP>1</SUP> Departamento de Microbiolog?a, Universidad de Granada, Granada, Spain<SUP>2</SUP>
Received 30 March 2007/ Returned for modification 26 April 2007/ Accepted 16 July 2007 <!-- ABS -->Influenza surveillance networks must detect early the viruses<SUP> </SUP>that will cause the forthcoming annual epidemics and isolate<SUP> </SUP>the strains for further characterization. We obtained the highest<SUP> </SUP>sensitivity (95.4%) with a diagnostic tool that combined a shell-vial<SUP> </SUP>assay and reverse transcription-PCR on cell culture supernatants<SUP> </SUP>at 48 h, and indeed, recovered the strain.<SUP> </SUP>
<SUP></SUP>
http://jcm.asm.org/cgi/content/abstract/45/9/3109