tetano
Editor, Senior Moderator
Diagn Interv Radiol
. 2023 Jan 16.
doi: 10.4274/dir.2022.221575. Online ahead of print.
Evaluation of abdominal computed tomography findings in patients with COVID-19: a multicenter study
Mehmet Ruhi Onur[SUP] 1 [/SUP], Yakup Özbay[SUP] 1 [/SUP], İlkay İdilman[SUP] 1 [/SUP], Ali Devrim Karaosmanoğlu[SUP] 1 [/SUP], Selma Uysal Ramadan[SUP] 2 [/SUP], Funda Barlık[SUP] 3 [/SUP], Sonay Aydın[SUP] 4 [/SUP], Hüseyin Odaman[SUP] 3 [/SUP], Canan Altay[SUP] 3 [/SUP], Işıl Başara Akın[SUP] 3 [/SUP], Oğuz Dicle[SUP] 3 [/SUP], Özgür Appak[SUP] 5 [/SUP], Başak Gülpınar[SUP] 6 [/SUP], Ayşe Erden[SUP] 6 [/SUP], Sezer Kula[SUP] 6 [/SUP], Ayşegül Gürsöy Çoruh[SUP] 6 [/SUP], Diğdem Kuru Öz[SUP] 6 [/SUP], Melahat Kul[SUP] 6 [/SUP], Çağlar Uzun[SUP] 6 [/SUP], Erdal Karavaş[SUP] 4 [/SUP], Akın Levent[SUP] 4 [/SUP], Hakan Artaş[SUP] 7 [/SUP], Hasan Eryeşil[SUP] 7 [/SUP], Onur Solmaz[SUP] 7 [/SUP], Türkkan Öztürk Kaygusuz[SUP] 8 [/SUP], Mustafa Faraşat[SUP] 9 [/SUP], Ahmet Burak Kale[SUP] 9 [/SUP], Fatih Düzgün[SUP] 9 [/SUP], Gökhan Pekindil[SUP] 9 [/SUP], F Demir Apaydın[SUP] 10 [/SUP], Meltem Nass Duce[SUP] 10 [/SUP], Yüksel Balcı[SUP] 10 [/SUP], Kaan Esen[SUP] 10 [/SUP], Ayşegül Sağır Kahraman[SUP] 11 [/SUP], Leyla Karaca[SUP] 11 [/SUP], Zeynep Maraş Özdemir[SUP] 11 [/SUP], Bayram Kahraman[SUP] 12 [/SUP], Mesude Tosun[SUP] 13 [/SUP], Mehmet Selim Nural[SUP] 14 [/SUP], İlkay Çamlıdağ[SUP] 14 [/SUP], Mustafa Arda Onar[SUP] 14 [/SUP], Kaan Ballı[SUP] 15 [/SUP], Ezgi Güler[SUP] 15 [/SUP], Mustafa Harman[SUP] 15 [/SUP], Nevra Zehra Elmas[SUP] 15 [/SUP], Cansu Öztürk[SUP] 2 [/SUP], Özlem Güngör[SUP] 2 [/SUP], Duygu Herek[SUP] 16 [/SUP], Ahmet Baki Yağcı[SUP] 16 [/SUP], Cengiz Erol[SUP] 17 [/SUP], Mehmet Şeker[SUP] 17 [/SUP], İrem İşlek[SUP] 17 [/SUP], Yusuf Can[SUP] 17 [/SUP], Serdar Aslan[SUP] 18 [/SUP], M Yasemin Karadeniz Bilgili[SUP] 19 [/SUP], Alper Göncüoğlu[SUP] 20 [/SUP], Hatice Keleş[SUP] 21 [/SUP], Pelin Zeynep Bekin Sarıkaya[SUP] 20 [/SUP], Barış Bakır[SUP] 22 [/SUP], Merve Gülbiz Dağoğlu Kartal[SUP] 22 [/SUP], Görkem Durak[SUP] 22 [/SUP], Gülşen Yücel Oğuzdoğan[SUP] 23 [/SUP], Fatih Alper[SUP] 24 [/SUP], Ahmet Yalçın[SUP] 24 [/SUP], Safiye Gürel[SUP] 25 [/SUP], Bircan Alan[SUP] 25 [/SUP], Elif Gündoğdu[SUP] 26 [/SUP], Nevin Aydın[SUP] 26 [/SUP], Ayşegül Cansu[SUP] 27 [/SUP], Ceyda Civan Kuş[SUP] 28 [/SUP], Elif Ofluoğlu Tuncer[SUP] 29 [/SUP], Ferhat Can Pişkin[SUP] 30 [/SUP], Hale Çolakoğlu Er[SUP] 31 [/SUP], Bumin Değirmenci[SUP] 32 [/SUP], Mustafa Nasuh Özmen[SUP] 1 [/SUP], Mecit Kantarcı[SUP] 4 [/SUP], Muşturay Karçaaltıncaba[SUP] 1 [/SUP]
Affiliations
Abstract
Purpose: To evaluate the frequency of abdominal computed tomography (CT) findings in patients with coronavirus disease-2019 (COVID-19) and interrogate the relationship between abdominal CT findings and patient demographic features, clinical findings, and laboratory test results as well as the CT atherosclerosis score in the abdominal aorta.
Methods: This study was designed as a multicenter retrospective study. The abdominal CT findings of 1.181 patients with positive abdominal symptoms from 26 tertiary medical centers with a positive polymerase chain-reaction test for severe acute respiratory syndrome coronavirus 2 were reviewed. The frequency of ischemic and non-ischemic CT findings as well as the association between CT findings, clinical features, and abdominal aortic calcific atherosclerosis score (AA-CAS) were recorded.
Results: Ischemic and non-ischemic abdominal CT findings were detected in 240 (20.3%) and 328 (27.7%) patients, respectively. In 147 patients (12.4%), intra-abdominal malignancy was present. The most frequent ischemic abdominal CT findings were bowel wall thickening (n = 120; 10.2%) and perivascular infiltration (n = 40; 3.4%). As for non-ischemic findings, colitis (n = 91; 7.7%) and small bowel inflammation (n = 73; 6.2%) constituted the most frequent disease processes. The duration of hospital stay was found to be higher in patients with abdominal CT findings than in patients without any positive findings (13.8 ± 13 vs. 10.4 ± 12.8 days, P < 0.001). The frequency of abdominal CT findings was significantly higher in patients who did not survive the infection than in patients who were discharged after recovery (41.7% vs. 27.4%, P < 0.001). Increased AA-CAS was found to be associated with a higher risk of ischemic conditions in abdominal CT examinations.
Conclusion: Abdominal symptoms in patients with COVID-19 are usually associated with positive CT findings. The presence of ischemic findings on CT correlates with poor COVID-19 outcomes. A high AA-CAS is associated with abdominal ischemic findings in patients with COVID-19.
Keywords: COVID-19; abdomen; abdominal aorta; arteriosclerosis; computed tomography.
. 2023 Jan 16.
doi: 10.4274/dir.2022.221575. Online ahead of print.
Evaluation of abdominal computed tomography findings in patients with COVID-19: a multicenter study
Mehmet Ruhi Onur[SUP] 1 [/SUP], Yakup Özbay[SUP] 1 [/SUP], İlkay İdilman[SUP] 1 [/SUP], Ali Devrim Karaosmanoğlu[SUP] 1 [/SUP], Selma Uysal Ramadan[SUP] 2 [/SUP], Funda Barlık[SUP] 3 [/SUP], Sonay Aydın[SUP] 4 [/SUP], Hüseyin Odaman[SUP] 3 [/SUP], Canan Altay[SUP] 3 [/SUP], Işıl Başara Akın[SUP] 3 [/SUP], Oğuz Dicle[SUP] 3 [/SUP], Özgür Appak[SUP] 5 [/SUP], Başak Gülpınar[SUP] 6 [/SUP], Ayşe Erden[SUP] 6 [/SUP], Sezer Kula[SUP] 6 [/SUP], Ayşegül Gürsöy Çoruh[SUP] 6 [/SUP], Diğdem Kuru Öz[SUP] 6 [/SUP], Melahat Kul[SUP] 6 [/SUP], Çağlar Uzun[SUP] 6 [/SUP], Erdal Karavaş[SUP] 4 [/SUP], Akın Levent[SUP] 4 [/SUP], Hakan Artaş[SUP] 7 [/SUP], Hasan Eryeşil[SUP] 7 [/SUP], Onur Solmaz[SUP] 7 [/SUP], Türkkan Öztürk Kaygusuz[SUP] 8 [/SUP], Mustafa Faraşat[SUP] 9 [/SUP], Ahmet Burak Kale[SUP] 9 [/SUP], Fatih Düzgün[SUP] 9 [/SUP], Gökhan Pekindil[SUP] 9 [/SUP], F Demir Apaydın[SUP] 10 [/SUP], Meltem Nass Duce[SUP] 10 [/SUP], Yüksel Balcı[SUP] 10 [/SUP], Kaan Esen[SUP] 10 [/SUP], Ayşegül Sağır Kahraman[SUP] 11 [/SUP], Leyla Karaca[SUP] 11 [/SUP], Zeynep Maraş Özdemir[SUP] 11 [/SUP], Bayram Kahraman[SUP] 12 [/SUP], Mesude Tosun[SUP] 13 [/SUP], Mehmet Selim Nural[SUP] 14 [/SUP], İlkay Çamlıdağ[SUP] 14 [/SUP], Mustafa Arda Onar[SUP] 14 [/SUP], Kaan Ballı[SUP] 15 [/SUP], Ezgi Güler[SUP] 15 [/SUP], Mustafa Harman[SUP] 15 [/SUP], Nevra Zehra Elmas[SUP] 15 [/SUP], Cansu Öztürk[SUP] 2 [/SUP], Özlem Güngör[SUP] 2 [/SUP], Duygu Herek[SUP] 16 [/SUP], Ahmet Baki Yağcı[SUP] 16 [/SUP], Cengiz Erol[SUP] 17 [/SUP], Mehmet Şeker[SUP] 17 [/SUP], İrem İşlek[SUP] 17 [/SUP], Yusuf Can[SUP] 17 [/SUP], Serdar Aslan[SUP] 18 [/SUP], M Yasemin Karadeniz Bilgili[SUP] 19 [/SUP], Alper Göncüoğlu[SUP] 20 [/SUP], Hatice Keleş[SUP] 21 [/SUP], Pelin Zeynep Bekin Sarıkaya[SUP] 20 [/SUP], Barış Bakır[SUP] 22 [/SUP], Merve Gülbiz Dağoğlu Kartal[SUP] 22 [/SUP], Görkem Durak[SUP] 22 [/SUP], Gülşen Yücel Oğuzdoğan[SUP] 23 [/SUP], Fatih Alper[SUP] 24 [/SUP], Ahmet Yalçın[SUP] 24 [/SUP], Safiye Gürel[SUP] 25 [/SUP], Bircan Alan[SUP] 25 [/SUP], Elif Gündoğdu[SUP] 26 [/SUP], Nevin Aydın[SUP] 26 [/SUP], Ayşegül Cansu[SUP] 27 [/SUP], Ceyda Civan Kuş[SUP] 28 [/SUP], Elif Ofluoğlu Tuncer[SUP] 29 [/SUP], Ferhat Can Pişkin[SUP] 30 [/SUP], Hale Çolakoğlu Er[SUP] 31 [/SUP], Bumin Değirmenci[SUP] 32 [/SUP], Mustafa Nasuh Özmen[SUP] 1 [/SUP], Mecit Kantarcı[SUP] 4 [/SUP], Muşturay Karçaaltıncaba[SUP] 1 [/SUP]
Affiliations
- PMID: 36960669
- DOI: 10.4274/dir.2022.221575
Abstract
Purpose: To evaluate the frequency of abdominal computed tomography (CT) findings in patients with coronavirus disease-2019 (COVID-19) and interrogate the relationship between abdominal CT findings and patient demographic features, clinical findings, and laboratory test results as well as the CT atherosclerosis score in the abdominal aorta.
Methods: This study was designed as a multicenter retrospective study. The abdominal CT findings of 1.181 patients with positive abdominal symptoms from 26 tertiary medical centers with a positive polymerase chain-reaction test for severe acute respiratory syndrome coronavirus 2 were reviewed. The frequency of ischemic and non-ischemic CT findings as well as the association between CT findings, clinical features, and abdominal aortic calcific atherosclerosis score (AA-CAS) were recorded.
Results: Ischemic and non-ischemic abdominal CT findings were detected in 240 (20.3%) and 328 (27.7%) patients, respectively. In 147 patients (12.4%), intra-abdominal malignancy was present. The most frequent ischemic abdominal CT findings were bowel wall thickening (n = 120; 10.2%) and perivascular infiltration (n = 40; 3.4%). As for non-ischemic findings, colitis (n = 91; 7.7%) and small bowel inflammation (n = 73; 6.2%) constituted the most frequent disease processes. The duration of hospital stay was found to be higher in patients with abdominal CT findings than in patients without any positive findings (13.8 ± 13 vs. 10.4 ± 12.8 days, P < 0.001). The frequency of abdominal CT findings was significantly higher in patients who did not survive the infection than in patients who were discharged after recovery (41.7% vs. 27.4%, P < 0.001). Increased AA-CAS was found to be associated with a higher risk of ischemic conditions in abdominal CT examinations.
Conclusion: Abdominal symptoms in patients with COVID-19 are usually associated with positive CT findings. The presence of ischemic findings on CT correlates with poor COVID-19 outcomes. A high AA-CAS is associated with abdominal ischemic findings in patients with COVID-19.
Keywords: COVID-19; abdomen; abdominal aorta; arteriosclerosis; computed tomography.