tetano
Editor, Senior Moderator
Cureus
. 2022 Feb 25;14(2):e22614.
doi: 10.7759/cureus.22614. eCollection 2022 Feb.
The Treatment of COVID-19 Purgatory Syndrome With Tocilizumab and Steroids
Vijairam Selvaraj[SUP] 1 [/SUP], Arkadiy Finn[SUP] 2 [/SUP], Jennifer Li[SUP] 3 [/SUP], Kwame Dapaah-Afriyie[SUP] 2 [/SUP]
Affiliations
Abstract
Hyperinflammation is a key component of severe coronavirus disease 2019 (COVID-19) and is associated with poor outcomes. It is imperative to distinguish severe COVID-19 from hyperinflammatory syndromes such as multisystem inflammatory syndrome (MIS) and hemophagocytic lymphohistiocytosis. There is a subset of post-COVID-19 patients who present with some symptoms characteristic of MIS in adults (MIS-A) yet do not meet all the criteria for a diagnosis. We describe the unique case of a patient with this kind of presentation who clinically improved following tocilizumab and corticosteroid usage.
Keywords: chis; covid; covid19; covid19 purgatory syndrome; cps; hyperinflammation; hyperinflammatory syndrome; mis-a; sars-cov-2; sars-cov2.
. 2022 Feb 25;14(2):e22614.
doi: 10.7759/cureus.22614. eCollection 2022 Feb.
The Treatment of COVID-19 Purgatory Syndrome With Tocilizumab and Steroids
Vijairam Selvaraj[SUP] 1 [/SUP], Arkadiy Finn[SUP] 2 [/SUP], Jennifer Li[SUP] 3 [/SUP], Kwame Dapaah-Afriyie[SUP] 2 [/SUP]
Affiliations
- PMID: 35371682
- PMCID: PMC8958274
- DOI: 10.7759/cureus.22614
Abstract
Hyperinflammation is a key component of severe coronavirus disease 2019 (COVID-19) and is associated with poor outcomes. It is imperative to distinguish severe COVID-19 from hyperinflammatory syndromes such as multisystem inflammatory syndrome (MIS) and hemophagocytic lymphohistiocytosis. There is a subset of post-COVID-19 patients who present with some symptoms characteristic of MIS in adults (MIS-A) yet do not meet all the criteria for a diagnosis. We describe the unique case of a patient with this kind of presentation who clinically improved following tocilizumab and corticosteroid usage.
Keywords: chis; covid; covid19; covid19 purgatory syndrome; cps; hyperinflammation; hyperinflammatory syndrome; mis-a; sars-cov-2; sars-cov2.