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Cureus . Review of Impact of COVID-19 on Maternal, Neonatal Outcomes, and Placental Changes

tetano

Editor, Senior Moderator
Cureus


. 2022 Aug 31;14(8):e28631.
doi: 10.7759/cureus.28631. eCollection 2022 Aug.
Review of Impact of COVID-19 on Maternal, Neonatal Outcomes, and Placental Changes


Resham Tanna[SUP] 1 [/SUP], Henry J Nava Dugarte[SUP] 2 [/SUP], Sowjanya Kurakula[SUP] 3 4 5 6 [/SUP], Vandana Muralidharan[SUP] 7 [/SUP], Arghadip Das[SUP] 8 [/SUP], Sri Padma Ravali Kanigalpula[SUP] 9 [/SUP], Ileana Elita Mendez[SUP] 10 [/SUP], Munaza Afaq[SUP] 11 [/SUP], Radhika Bassi[SUP] 12 [/SUP], Kinjal Shah[SUP] 13 [/SUP], Zainab Saddiq[SUP] 14 [/SUP]



Affiliations

Abstract

Coronavirus disease (COVID-19), caused by SARS-CoV-2, is a disease that has caused a global impact. COVID-19 is transmitted through airborne droplets, respiratory secretions, and direct contact. The pandemic has affected individuals of different ages, and studying the impact of COVID-19 on maternal and newborn outcomes is critical. In this review, we highlight the impact of COVID-19 infection in pregnancy and its repercussion in the maternal-fetal binomial. Physiological changes that occur during pregnancy have significant effects on the immune system, cardiopulmonary system, and coagulation, and these changes can result in an altered response to COVID-19 infection. The symptoms, risk factors, and maternal health consequences of COVID-19 were discussed. In addition, the impact of newborns born to mothers with COVID-19 was reviewed. Finally, placental changes and vertical transmission of COVID-19 during pregnancy were also discussed in this review.

Keywords: covid-19; maternal outcomes; neonatal outcomes; placental changes; pregnancy.
 
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