tetano
Editor, Senior Moderator
Cureus
. 2025 Feb 23;17(2):e79517.
doi: 10.7759/cureus.79517. eCollection 2025 Feb. Autoimmune Rhombencephalitis as a Presentation of Post-COVID-19 Syndrome: A Case Report
Alaa S Mohamed[SUP] 1 [/SUP], Neesha Jahani[SUP] 2 [/SUP], Mingyu Li[SUP] 2 [/SUP], Manan Shah[SUP] 2 [/SUP], Askiel Bruno[SUP] 2 [/SUP], Dilip Singh[SUP] 2 [/SUP]
Affiliations
There has been a multitude of neurological sequelae associated with the 2019 SARS-CoV-2 outbreak. We describe a unique case of a 31-year-old individual who developed post-infectious autoimmune rhombencephalitis approximately two weeks after testing positive for coronavirus disease 2019 (COVID-19). Treatment with high-dose corticosteroids with four weeks of taper resulted in excellent clinical recovery without any relapse. Thus, our findings support the use of immunotherapy as a potential treatment in cases of post-COVID-19 autoimmune rhombencephalitis. Furthermore, this case highlights the importance of considering post-infectious COVID-19 sequelae as a differential diagnosis in patients presenting with rhombencephalitis in the appropriate clinical setting.
Keywords: autoimmune; brain stem; cerebellum; covid 19; post-covid-19; rhombencephalitis; sars-cov.
. 2025 Feb 23;17(2):e79517.
doi: 10.7759/cureus.79517. eCollection 2025 Feb. Autoimmune Rhombencephalitis as a Presentation of Post-COVID-19 Syndrome: A Case Report
Alaa S Mohamed[SUP] 1 [/SUP], Neesha Jahani[SUP] 2 [/SUP], Mingyu Li[SUP] 2 [/SUP], Manan Shah[SUP] 2 [/SUP], Askiel Bruno[SUP] 2 [/SUP], Dilip Singh[SUP] 2 [/SUP]
Affiliations
- PMID: 40135036
- PMCID: PMC11936410
- DOI: 10.7759/cureus.79517
There has been a multitude of neurological sequelae associated with the 2019 SARS-CoV-2 outbreak. We describe a unique case of a 31-year-old individual who developed post-infectious autoimmune rhombencephalitis approximately two weeks after testing positive for coronavirus disease 2019 (COVID-19). Treatment with high-dose corticosteroids with four weeks of taper resulted in excellent clinical recovery without any relapse. Thus, our findings support the use of immunotherapy as a potential treatment in cases of post-COVID-19 autoimmune rhombencephalitis. Furthermore, this case highlights the importance of considering post-infectious COVID-19 sequelae as a differential diagnosis in patients presenting with rhombencephalitis in the appropriate clinical setting.
Keywords: autoimmune; brain stem; cerebellum; covid 19; post-covid-19; rhombencephalitis; sars-cov.