tetano
Editor, Senior Moderator
Cureus
. 2022 Jul 2;14(7):e26519.
doi: 10.7759/cureus.26519. eCollection 2022 Jul.
An Early Catch: Multisystem Inflammatory Syndrome in Adults (MIS-A) in a Young Adult Male With COVID-19 Exposure
Farzam Khokhar[SUP] 1 [/SUP], Zainab Bhura[SUP] 2 [/SUP], Muhammad Muneeb[SUP] 3 [/SUP], Garima Singh[SUP] 4 [/SUP], Jianghong Yu[SUP] 5 [/SUP]
Affiliations
Abstract
While severe acute respiratory syndrome (SARS) is the most common presentation of coronavirus disease 2019 (COVID-19) infection, several short- and long-term complications from COVID-19 infection are also being recognized. One such complication with life-threatening consequences is known as multisystem inflammatory syndrome in adults (MIS-A). While the phenomenon of multisystem inflammatory syndrome in children (MIS-C) is more recognized, the pathophysiology of both presentations remains a mystery currently. Several theories have been put forward however no consensus has been established yet. We present the case of a 20-year-old male who was admitted to the intensive care unit for a multisystem illness characterized by severe biventricular failure, profound shock, and acute liver and kidney injuries. The severity of illness necessitated the treatment with mechanical ventilation, extracorporeal membrane oxygenation (ECMO), vasopressors, and continuous veno-venous hemofiltration (CVVH). The patient was treated with one dose of intravenous immune globulin (IVIG). In association with the foregoing treatment, the patient made dramatic recovery and came off pulmonary, hemodynamic, and renal support within a week and made remarkably quick and full recovery. This case highlights a rare presentation of a COVID-19 complication that requires prompt recognition, supportive care, and empiric treatment that led to a favorable outcome in this case.
Keywords: academic rheumatology; covid 19; internal medicine and rheumatology; intravenous immune globulin; multisystem inflammatory syndrome; multisystem inflammatory syndrome in adult; multisystem inflammatory syndrome in children; pulmonary critical care; sars-cov-2; vv ecmo.
. 2022 Jul 2;14(7):e26519.
doi: 10.7759/cureus.26519. eCollection 2022 Jul.
An Early Catch: Multisystem Inflammatory Syndrome in Adults (MIS-A) in a Young Adult Male With COVID-19 Exposure
Farzam Khokhar[SUP] 1 [/SUP], Zainab Bhura[SUP] 2 [/SUP], Muhammad Muneeb[SUP] 3 [/SUP], Garima Singh[SUP] 4 [/SUP], Jianghong Yu[SUP] 5 [/SUP]
Affiliations
- PMID: 35815299
- PMCID: PMC9259070
- DOI: 10.7759/cureus.26519
Abstract
While severe acute respiratory syndrome (SARS) is the most common presentation of coronavirus disease 2019 (COVID-19) infection, several short- and long-term complications from COVID-19 infection are also being recognized. One such complication with life-threatening consequences is known as multisystem inflammatory syndrome in adults (MIS-A). While the phenomenon of multisystem inflammatory syndrome in children (MIS-C) is more recognized, the pathophysiology of both presentations remains a mystery currently. Several theories have been put forward however no consensus has been established yet. We present the case of a 20-year-old male who was admitted to the intensive care unit for a multisystem illness characterized by severe biventricular failure, profound shock, and acute liver and kidney injuries. The severity of illness necessitated the treatment with mechanical ventilation, extracorporeal membrane oxygenation (ECMO), vasopressors, and continuous veno-venous hemofiltration (CVVH). The patient was treated with one dose of intravenous immune globulin (IVIG). In association with the foregoing treatment, the patient made dramatic recovery and came off pulmonary, hemodynamic, and renal support within a week and made remarkably quick and full recovery. This case highlights a rare presentation of a COVID-19 complication that requires prompt recognition, supportive care, and empiric treatment that led to a favorable outcome in this case.
Keywords: academic rheumatology; covid 19; internal medicine and rheumatology; intravenous immune globulin; multisystem inflammatory syndrome; multisystem inflammatory syndrome in adult; multisystem inflammatory syndrome in children; pulmonary critical care; sars-cov-2; vv ecmo.