tetano
Editor, Senior Moderator
Pediatr Int. 2011 Jan 25. doi: 10.1111/j.1442-200X.2011.03324.x. [Epub ahead of print]
Critical findings of severe influenza A (H1N1) pneumonia in children.
Ishigaki H, Sai S, Shirai M, Hongo T.
Department in which the work was performed: Department of Pediatrics, Iwata City Hospital, 512-3 Okubo, Iwata 438-8550, Japan.
Abstract
Background: Pandemic influenza A (H1N1) cause severe pneumonia in children. However the mechanism how some pneumonia patients would develop respiratory failure remained unknown. This report describes clinical features of childhood influenza A pneumonia patients. Methods: We reviewed the clinical and laboratory findings of 31 H1N1 pneumonia patients who are hospitalized in Iwata City Hospital from October 1, 2009, to January 31, 2010. Intubation and mechanical ventilation were required due to developing respiratory failure for 8 patients who were classified into intubation group. Other patients without mechanical ventilation were classified into non-intubation group. Clinical features and laboratory findings were compared between the two groups. Results: The median age was 6.3 (range, 3-10) years. The male to female ratio was 22:9. Clinical manifestations of tachycardia, tachypnea and cyanosis were significant findings in intubation group at admission. Lymphocytopenia was observed in both groups. Leukocytosis with neutrophilia was the risk factor for intubation. Conclusions: These findings could be useful predictors at admission to identify the high risk pneumonia patients of influenza A (H1N1) in children.
? 2011 The Authors. Pediatrics International ? 2011 Japan Pediatric Society.
PMID: 21261785 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21261785
Critical findings of severe influenza A (H1N1) pneumonia in children.
Ishigaki H, Sai S, Shirai M, Hongo T.
Department in which the work was performed: Department of Pediatrics, Iwata City Hospital, 512-3 Okubo, Iwata 438-8550, Japan.
Abstract
Background: Pandemic influenza A (H1N1) cause severe pneumonia in children. However the mechanism how some pneumonia patients would develop respiratory failure remained unknown. This report describes clinical features of childhood influenza A pneumonia patients. Methods: We reviewed the clinical and laboratory findings of 31 H1N1 pneumonia patients who are hospitalized in Iwata City Hospital from October 1, 2009, to January 31, 2010. Intubation and mechanical ventilation were required due to developing respiratory failure for 8 patients who were classified into intubation group. Other patients without mechanical ventilation were classified into non-intubation group. Clinical features and laboratory findings were compared between the two groups. Results: The median age was 6.3 (range, 3-10) years. The male to female ratio was 22:9. Clinical manifestations of tachycardia, tachypnea and cyanosis were significant findings in intubation group at admission. Lymphocytopenia was observed in both groups. Leukocytosis with neutrophilia was the risk factor for intubation. Conclusions: These findings could be useful predictors at admission to identify the high risk pneumonia patients of influenza A (H1N1) in children.
? 2011 The Authors. Pediatrics International ? 2011 Japan Pediatric Society.
PMID: 21261785 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21261785