Emily
Editor, Senior Moderator
https://elifesciences.org/articles/69496
eLife 2021;10:e69496 doi: 10.7554/eLife.69496
COVID-19: Avoiding culture shock with the SARS-CoV-2 spike protein
Main text
Researchers across the globe are frantically trying to understand the biology of different SARS-CoV-2 variants to develop new therapeutics and bring the COVID-19 pandemic to an end. The process begins in the laboratory, with painstaking experiments to judge whether a drug can stop SARS-CoV-2 from replicating in cells in a dish, or whether a vaccine can stop an animal from getting sick. But such experiments require copious amounts of SARS-CoV-2, and the authenticity of that virus stock (which is usually cultured in animal cell lines) is paramount to ensure the validity of test results...
eLife 2021;10:e69496 doi: 10.7554/eLife.69496
COVID-19: Avoiding culture shock with the SARS-CoV-2 spike protein
- Institute of Medical Virology, University of Zurich, Switzerland
Main text
Researchers across the globe are frantically trying to understand the biology of different SARS-CoV-2 variants to develop new therapeutics and bring the COVID-19 pandemic to an end. The process begins in the laboratory, with painstaking experiments to judge whether a drug can stop SARS-CoV-2 from replicating in cells in a dish, or whether a vaccine can stop an animal from getting sick. But such experiments require copious amounts of SARS-CoV-2, and the authenticity of that virus stock (which is usually cultured in animal cell lines) is paramount to ensure the validity of test results...