tetano
Editor, Senior Moderator
Rev Panam Salud Publica. 2012 Jun;31(6):447-53.
[Cost-effectiveness of vaccinating pregnant women against pandemic influenza in Colombia].
[Article in Spanish]
Chocont?-Piraquive LA, Alvis Guzm?n N, De la Hoz Restrepo F.
Source
Grupo de Epidemiolog?a y Evaluaci?n en Salud P?blica, Facultad de Medicina, Universidad Nacional de Colombia, Bogot?, D.C., Colombia.
Abstract
OBJECTIVE:
Estimating the cost-effectiveness ratio of vaccinating pregnant women against the 2009 pandemic influenza A (H1N1) in Colombia during the second wave of the pandemic.
METHODS:
A decision tree was constructed, which simulated the health results (deaths and years of potential life lost [YPLL]) in two cohorts of pregnant women; one vaccinated, the other unvaccinated. The model's parameters were drawn from scientific literature and costs were estimated on the basis of a previous study. Incremental cost-effectiveness ratios (ICER) were calculated.
RESULTS:
Vaccinating pregnant women against pandemic flu would have prevented between 4 664 and 15 741 outpatient visits and between 119 and 401 hospitalizations. Between US$ 249 530 and US$ 842 163 in costs of care would have been avoided. For the base scenario, vaccinating pregnant women would be cost-effective (ICER/YPLL avoided US$ 7 657). This ICER was responsive to the disease's fatality rate; vaccina tion would not be cost-effective in Colombia in scenarios with a lower fatality rate.
CONCLUSIONS:
Vaccinating pregnant women against pandemic influenza is cost-effective in a scenario with a high mortality rate. The existing evidence that pregnant women are at increased risk of complications and that the vaccine is safe would justify its use in pregnant women.
PMID:
22858810
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/22858810
[Cost-effectiveness of vaccinating pregnant women against pandemic influenza in Colombia].
[Article in Spanish]
Chocont?-Piraquive LA, Alvis Guzm?n N, De la Hoz Restrepo F.
Source
Grupo de Epidemiolog?a y Evaluaci?n en Salud P?blica, Facultad de Medicina, Universidad Nacional de Colombia, Bogot?, D.C., Colombia.
Abstract
OBJECTIVE:
Estimating the cost-effectiveness ratio of vaccinating pregnant women against the 2009 pandemic influenza A (H1N1) in Colombia during the second wave of the pandemic.
METHODS:
A decision tree was constructed, which simulated the health results (deaths and years of potential life lost [YPLL]) in two cohorts of pregnant women; one vaccinated, the other unvaccinated. The model's parameters were drawn from scientific literature and costs were estimated on the basis of a previous study. Incremental cost-effectiveness ratios (ICER) were calculated.
RESULTS:
Vaccinating pregnant women against pandemic flu would have prevented between 4 664 and 15 741 outpatient visits and between 119 and 401 hospitalizations. Between US$ 249 530 and US$ 842 163 in costs of care would have been avoided. For the base scenario, vaccinating pregnant women would be cost-effective (ICER/YPLL avoided US$ 7 657). This ICER was responsive to the disease's fatality rate; vaccina tion would not be cost-effective in Colombia in scenarios with a lower fatality rate.
CONCLUSIONS:
Vaccinating pregnant women against pandemic influenza is cost-effective in a scenario with a high mortality rate. The existing evidence that pregnant women are at increased risk of complications and that the vaccine is safe would justify its use in pregnant women.
PMID:
22858810
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/22858810