tetano
Editor, Senior Moderator
J Med Virol. 2018 Mar 25. doi: 10.1002/jmv.25077. [Epub ahead of print]
[h=1]Corticosteroid therapy in Pneumonia from Swine-Origin Influenza A (H1N1) in China.[/h] Jia Y[SUP]1[/SUP], Liao Y[SUP]1[/SUP], Shao L[SUP]1[/SUP], Du L[SUP]1[/SUP], Wang B[SUP]1[/SUP], Su D[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Background The first three cases of confirmed infection with the virus in China were documented between May 10 and May 15, 2009. Although the clinical characteristics of the H1N1 pneumonia were described in clinical reports, the therapy has few been described. Therefore, we report our experiences of 53 cases of the H1N1 pneumonia with treatment. Methods We describe clinical characteristic of 53 patients who were hospitalized for laboratory-confirmed H1N1 pneumonia at the 2nd Clinical College of Harbin Medical University. In addition, we measure the role of corticosteroid, mechanical ventilation, and noncorticosteroid antiviral therapy in the management of pneumonia patients with novel H1N1 infection. Real-time reverse-transcriptase-polymerase chain (RT-PCR) testing was used to confirm infection. Results The outcome of therapy was compared in scores of PaO[SUB]2[/SUB] and CT. The data was statistical analyzed by the Shapiro-Wilk, anova, Student-Newman-Keuls Test and Kruskal-Wallis Test. Conclusions The most common symptoms were dyspnea. In moderate ill patients, the changes in the increased PaO[SUB]2[/SUB] were lower in the noncorticosteroid antiviral therapy group than in the combination of corticosteroid and noncorticosteroid antiviral therapy after 5 days' therapy. The therapy protocol of noncorticosteriod +mechanical ventilation played important role in the recovery of severe ill patients. This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] H1N1; antiviral; pneumonia; therapy
PMID: 29574888 DOI: 10.1002/jmv.25077
[h=1]Corticosteroid therapy in Pneumonia from Swine-Origin Influenza A (H1N1) in China.[/h] Jia Y[SUP]1[/SUP], Liao Y[SUP]1[/SUP], Shao L[SUP]1[/SUP], Du L[SUP]1[/SUP], Wang B[SUP]1[/SUP], Su D[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Background The first three cases of confirmed infection with the virus in China were documented between May 10 and May 15, 2009. Although the clinical characteristics of the H1N1 pneumonia were described in clinical reports, the therapy has few been described. Therefore, we report our experiences of 53 cases of the H1N1 pneumonia with treatment. Methods We describe clinical characteristic of 53 patients who were hospitalized for laboratory-confirmed H1N1 pneumonia at the 2nd Clinical College of Harbin Medical University. In addition, we measure the role of corticosteroid, mechanical ventilation, and noncorticosteroid antiviral therapy in the management of pneumonia patients with novel H1N1 infection. Real-time reverse-transcriptase-polymerase chain (RT-PCR) testing was used to confirm infection. Results The outcome of therapy was compared in scores of PaO[SUB]2[/SUB] and CT. The data was statistical analyzed by the Shapiro-Wilk, anova, Student-Newman-Keuls Test and Kruskal-Wallis Test. Conclusions The most common symptoms were dyspnea. In moderate ill patients, the changes in the increased PaO[SUB]2[/SUB] were lower in the noncorticosteroid antiviral therapy group than in the combination of corticosteroid and noncorticosteroid antiviral therapy after 5 days' therapy. The therapy protocol of noncorticosteriod +mechanical ventilation played important role in the recovery of severe ill patients. This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] H1N1; antiviral; pneumonia; therapy
PMID: 29574888 DOI: 10.1002/jmv.25077