Mary Wilson
Well-known member
28 Jul 2023
Vol 9, Issue 30
DOI: 10.1126/sciadv.adh5325
WENYA DU, LIN ZHANG, EMMA SUH, DABIN LIN, COLIN MARCUS, LARA OZKAN, AVANI AHUJA, SARA FERNANDEZ, IKRA IFTEKHAR SHUVO, [...], AND CANAN DAGDEVIREN
Abstract
Ultrasound is widely used for tissue imaging such as breast cancer diagnosis; however, fundamental challenges limit its integration with wearable technologies, namely, imaging over large-area curvilinear organs. We introduced a wearable, conformable ultrasound breast patch (cUSBr-Patch) that enables standardized and reproducible image acquisition over the entire breast with less reliance on operator training and applied transducer compression. A nature-inspired honeycomb-shaped patch combined with a phased array is guided by an easy-to-operate tracker that provides for large-area, deep scanning, and multiangle breast imaging capability. The in vitro studies and clinical trials reveal that the array using a piezoelectric crystal [Yb/Bi-Pb(In[SUB]1[/SUB][SUB]/2[/SUB]Nb[SUB]1/2[/SUB])O[SUB]3[/SUB]-Pb(Mg[SUB]1/[/SUB][SUB]3[/SUB]Nb[SUB]2/3[/SUB])O[SUB]3[/SUB]-PbTiO[SUB]3[/SUB]] (Yb/Bi-PIN-PMN-PT) exhibits a sufficient contrast resolution (~3 dB) and axial/lateral resolutions of 0.25/1.0 mm at 30 mm depth, allowing the observation of small cysts (~0.3 cm) in the breast. This research develops a first-of-its-kind ultrasound technology for breast tissue scanning and imaging that offers a noninvasive method for tracking real-time dynamic changes of soft tissue.
https://www.science.org/doi/10.1126/sciadv.adh5325
Vol 9, Issue 30
DOI: 10.1126/sciadv.adh5325
WENYA DU, LIN ZHANG, EMMA SUH, DABIN LIN, COLIN MARCUS, LARA OZKAN, AVANI AHUJA, SARA FERNANDEZ, IKRA IFTEKHAR SHUVO, [...], AND CANAN DAGDEVIREN
Abstract
Ultrasound is widely used for tissue imaging such as breast cancer diagnosis; however, fundamental challenges limit its integration with wearable technologies, namely, imaging over large-area curvilinear organs. We introduced a wearable, conformable ultrasound breast patch (cUSBr-Patch) that enables standardized and reproducible image acquisition over the entire breast with less reliance on operator training and applied transducer compression. A nature-inspired honeycomb-shaped patch combined with a phased array is guided by an easy-to-operate tracker that provides for large-area, deep scanning, and multiangle breast imaging capability. The in vitro studies and clinical trials reveal that the array using a piezoelectric crystal [Yb/Bi-Pb(In[SUB]1[/SUB][SUB]/2[/SUB]Nb[SUB]1/2[/SUB])O[SUB]3[/SUB]-Pb(Mg[SUB]1/[/SUB][SUB]3[/SUB]Nb[SUB]2/3[/SUB])O[SUB]3[/SUB]-PbTiO[SUB]3[/SUB]] (Yb/Bi-PIN-PMN-PT) exhibits a sufficient contrast resolution (~3 dB) and axial/lateral resolutions of 0.25/1.0 mm at 30 mm depth, allowing the observation of small cysts (~0.3 cm) in the breast. This research develops a first-of-its-kind ultrasound technology for breast tissue scanning and imaging that offers a noninvasive method for tracking real-time dynamic changes of soft tissue.
https://www.science.org/doi/10.1126/sciadv.adh5325