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Clinical characteristics and computed tomography findings in children with 2009 pandemic influenza A (H1N1) viral pneumonia

tetano

Editor, Senior Moderator
Scand J Infect Dis. 2010 Sep 21. [Epub ahead of print]
Clinical characteristics and computed tomography findings in children with 2009 pandemic influenza A (H1N1) viral pneumonia.

Mori T, Morii M, Terada K, Wada Y, Kuroiwa Y, Hotsubo T, Fuse S, Nishioka S, Nishioka T, Tsutsumi H.

Department of Paediatrics, NTT East Sapporo Hospital.
Abstract

Abstract In this article we review the clinical characteristics and computed tomography (CT) findings in children with 2009 pandemic H1N1 influenza viral pneumonia. The medical charts of 88 children with pandemic H1N1 influenza virus infection, admitted to our hospital in Japan from 10 August to 28 December 2009, were reviewed; we compared the clinical features of these children with those of 61 children admitted with seasonal influenza A during the previous 3 seasons. Of 88 patients, 53 (60%) had radiographic findings consistent with pneumonia and 34 patients underwent a chest computed tomography (CT) scan. Pneumonia was a more frequent complication in children with pandemic H1N1 influenza compared with those with seasonal influenza (60% vs 11%; p < 0.001). The predominant CT findings were unilateral or bilateral multifocal consolidation (15/34; 44%) associated with ground-glass opacities in the peribronchovascular region. The second most common CT finding was unilateral diffuse consolidation or atelectasis in 1 or more lung zones (12/34; 35%). The chest CT findings of unilateral or bilateral multifocal consolidation often associated with ground-glass opacities were commonly seen in children with pandemic H1N1 influenza viral pneumonia. Atelectasis was seen in patients who required oxygen administration.

PMID: 20854219 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/20854219
 
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