tetano
Editor, Senior Moderator
Clin Med (Lond)
. 2021 Mar;21(2):155-157.
doi: 10.7861/clinmed.2020-0940.
Lesson of the month: Severe leukoencephalopathy by SARS-CoV-2
Leticia Sanz-Canalejas[SUP] 1 [/SUP], Mar?a Del Carmen Polidura-Arruga[SUP] 2 [/SUP], Miguel Yus-Fuertes[SUP] 2 [/SUP], Manuela Jorquera-Moya[SUP] 2 [/SUP], Nieves Vidart-Sim?n[SUP] 2 [/SUP], Juan Arrazola-Garc?a[SUP] 2 [/SUP], Natividad G?mez-Ruiz[SUP] 2 [/SUP]
Affiliations
Abstract
Neurological manifestations associated with SARS-CoV-2 infection as well as its pathogenesis are insufficiently explained. We present two cases of severe COVID-19 who required hospitalisation in the intensive care unit with persistently depressed mental status and severe leukoencephalopathy. We discuss the clinical and radiological findings and also propose the possible pathogenesis involved.
Keywords: COVID-19; MRI; brain; coronavirus; leukoencephalopathy.
. 2021 Mar;21(2):155-157.
doi: 10.7861/clinmed.2020-0940.
Lesson of the month: Severe leukoencephalopathy by SARS-CoV-2
Leticia Sanz-Canalejas[SUP] 1 [/SUP], Mar?a Del Carmen Polidura-Arruga[SUP] 2 [/SUP], Miguel Yus-Fuertes[SUP] 2 [/SUP], Manuela Jorquera-Moya[SUP] 2 [/SUP], Nieves Vidart-Sim?n[SUP] 2 [/SUP], Juan Arrazola-Garc?a[SUP] 2 [/SUP], Natividad G?mez-Ruiz[SUP] 2 [/SUP]
Affiliations
- PMID: 33762380
- DOI: 10.7861/clinmed.2020-0940
Abstract
Neurological manifestations associated with SARS-CoV-2 infection as well as its pathogenesis are insufficiently explained. We present two cases of severe COVID-19 who required hospitalisation in the intensive care unit with persistently depressed mental status and severe leukoencephalopathy. We discuss the clinical and radiological findings and also propose the possible pathogenesis involved.
Keywords: COVID-19; MRI; brain; coronavirus; leukoencephalopathy.