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Clin Infect Dis Influenza Vaccine Does Not Increase the Risk of Coronavirus or Other Non-Influenza Respiratory Viruses: Retrospective Analysis From C

tetano

Editor, Senior Moderator
Clin Infect Dis


. 2020 May 22;ciaa626.
doi: 10.1093/cid/ciaa626. Online ahead of print.
Influenza Vaccine Does Not Increase the Risk of Coronavirus or Other Non-Influenza Respiratory Viruses: Retrospective Analysis From Canada, 2010-11 to 2016-17


Danuta M Skowronski[SUP] 1 2 [/SUP], Macy Zou[SUP] 1 [/SUP], Quinten Clarke[SUP] 1 [/SUP], Catharine Chambers[SUP] 1 [/SUP], James A Dickinson[SUP] 3 [/SUP], Suzana Sabaiduc[SUP] 1 [/SUP], Romy Olsha[SUP] 4 [/SUP], Jonathan B Gubbay[SUP] 4 5 [/SUP], Steven J Drews[SUP] 6 7 [/SUP], Hugues Charest[SUP] 8 [/SUP], Anne-Luise Winter[SUP] 4 [/SUP], Agatha Jassem[SUP] 1 2 [/SUP], Michelle Murti[SUP] 4 5 [/SUP], Mel Krajden[SUP] 1 2 [/SUP], Gaston De Serres[SUP] 8 9 10 [/SUP]



Affiliations

Abstract

Influenza vaccine effectiveness against influenza and non-influenza respiratory viruses (NIRV) was assessed by test-negative design using historic datasets of the community-based Canadian Sentinel Practitioner Surveillance Network (SPSN), spanning 2010-11 to 2016-17. Vaccine significantly reduced the risk of influenza illness by >40% with no effect on coronaviruses or other NIRV risk.

Keywords: coronavirus; influenza; non-specific immunity; respiratory viruses; vaccine effectiveness.
 
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