Clin Infect Dis. How Will Physicians Respond to the Next Influenza Pandemic?

Giuseppe · Oct 23, 2013

[Source: US National Library of Medicine, full page: (LINK). Abstract, edited.]

Clin Infect Dis. 2013 Oct 21. [Epub ahead of print]

How Will Physicians Respond to the Next Influenza Pandemic?

Fedson DS.

Abstract

The emergence of the H7N9 virus in China is another reminder of the threat of a global influenza pandemic. Many believe we could confront a pandemic by expanding our capacity to provide timely supplies of affordable pandemic vaccines and antiviral agents. Experience in 2009 demonstrated this can't and won't be done. Consequently, physicians may have little more to offer their patients than they had in the 1918 pandemic. Fortunately, several modern drugs (e.g., statins, ACE inhibitors, ARBs) can modify the host response to inflammatory illness, and laboratory and clinical studies suggest they might be used to treat pandemic patients. Unfortunately, little attention has been given to the research needed to support their use in patient care. There is no guarantee these drugs will work, but physicians will never know unless those responsible for pandemic preparedness recognize and act on the extraordinary possibility that they might save lives.

PMID: 24145877 [PubMed - as supplied by publisher]

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Laidback Al · Oct 24, 2013

Re: Clin Infect Dis. How Will Physicians Respond to the Next Influenza Pandemic?

Some FluTrackers links relevant to discussions with Dr. Fedson about the use of modern drugs in pandemic situations.

Dr. Fedson- consider statins - "Bird flu vaccine '10 years away' "
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FluTrackers Interviews David S. Fedson, M.D. - Meeting the Challenge of Influenza Pandemic Preparedness in Developing Countries

Treating Influenza with Statins and Other Immunomodulatory Agents
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Clin Infect Dis. How Will Physicians Respond to the Next Influenza Pandemic?

Giuseppe

Emeritus

Laidback Al

Well-known member