tetano
Editor, Senior Moderator
Clin Exp Vaccine Res
. 2022 Jan;11(1):89-95.
doi: 10.7774/cevr.2022.11.1.89. Epub 2022 Jan 31.
Factors associated with side effects of COVID-19 vaccine in Indonesia
Johan Wibowo[SUP] 1 [/SUP], Rivaldo Steven Heriyanto[SUP] 1 [/SUP], Felix Wijovi[SUP] 1 [/SUP], Devina Adella Halim[SUP] 1 [/SUP], Claudia Claudia[SUP] 1 [/SUP], Elizabeth Marcella[SUP] 1 [/SUP], Billy Susanto[SUP] 1 [/SUP], Michele Indrawan[SUP] 1 [/SUP], Nadia Khoirunnisa Heryadi[SUP] 1 [/SUP], Michelle Imanuelly[SUP] 1 [/SUP], Jonathan Juniard Anurantha[SUP] 1 [/SUP], Timotius Ivan Hariyanto[SUP] 1 [/SUP], Chintya Marcellin[SUP] 1 [/SUP], Terry Devita Sinaga[SUP] 1 [/SUP], Saraswati Anindita Rizki[SUP] 1 [/SUP], Novia Sieto[SUP] 1 [/SUP], Jeremia Immanuel Siregar[SUP] 2 [/SUP], Nata Pratama Hardjo Lugito[SUP] 2 [/SUP], Andree Kurniawan[SUP] 2 [/SUP]
Affiliations
Abstract
Purpose: As coronavirus disease 2019 (COVID-19) continues to spread rapidly causing approximately 186 million confirmed cases around the world, the urgency to reach herd immunity through vaccination is increasing. However, vaccine safety is a top priority to limit the occurrence of adverse events. Henceforth, this study aims to recognize and perceive COVID-19 vaccine safety in Indonesia during the pandemic.
Materials and methods: This is a cross-sectional study and was conducted in Indonesia during the COVID-19 pandemic using an online survey of demographic information and a qualitative questionnaire. Responses were recorded and the association between demographic characteristics from survey questions was tested using chi-square with a risk estimate and 95% confidence interval.
Results: A total of 311 participants from 33 out of 34 provinces in Indonesia participated in this study. Recorded responses showed multiple side effects of the COVID-19 vaccine both short- and long-term experienced by the participants. Significant associations were found between demographic factors and COVID-19 vaccine side effects such as female gender with short-term puncture site (odds ratio [OR], 0.463; 95% confidence interval [CI], 0.263-0.816) and short-term other reactions (OR, 0.463; 95% CI, 0.263-0.816), domicile outside Java island with long-term puncture site (OR, 4.219; 95% CI, 1.401-12.701) and immune reactions (OR, 3.375; 95% CI, 1.356-8.398), also between married marital status and long-term vagal reaction (OR, 4.655; 95% CI, 1.321-16.409).
Conclusion: Gender, domicile and marital status factors were associated with COVID-19 vaccine side effects in Indonesian people.
Keywords: COVID-19; Side effect; Vaccination; Vaccines.
. 2022 Jan;11(1):89-95.
doi: 10.7774/cevr.2022.11.1.89. Epub 2022 Jan 31.
Factors associated with side effects of COVID-19 vaccine in Indonesia
Johan Wibowo[SUP] 1 [/SUP], Rivaldo Steven Heriyanto[SUP] 1 [/SUP], Felix Wijovi[SUP] 1 [/SUP], Devina Adella Halim[SUP] 1 [/SUP], Claudia Claudia[SUP] 1 [/SUP], Elizabeth Marcella[SUP] 1 [/SUP], Billy Susanto[SUP] 1 [/SUP], Michele Indrawan[SUP] 1 [/SUP], Nadia Khoirunnisa Heryadi[SUP] 1 [/SUP], Michelle Imanuelly[SUP] 1 [/SUP], Jonathan Juniard Anurantha[SUP] 1 [/SUP], Timotius Ivan Hariyanto[SUP] 1 [/SUP], Chintya Marcellin[SUP] 1 [/SUP], Terry Devita Sinaga[SUP] 1 [/SUP], Saraswati Anindita Rizki[SUP] 1 [/SUP], Novia Sieto[SUP] 1 [/SUP], Jeremia Immanuel Siregar[SUP] 2 [/SUP], Nata Pratama Hardjo Lugito[SUP] 2 [/SUP], Andree Kurniawan[SUP] 2 [/SUP]
Affiliations
- PMID: 35223669
- PMCID: PMC8844667
- DOI: 10.7774/cevr.2022.11.1.89
Abstract
Purpose: As coronavirus disease 2019 (COVID-19) continues to spread rapidly causing approximately 186 million confirmed cases around the world, the urgency to reach herd immunity through vaccination is increasing. However, vaccine safety is a top priority to limit the occurrence of adverse events. Henceforth, this study aims to recognize and perceive COVID-19 vaccine safety in Indonesia during the pandemic.
Materials and methods: This is a cross-sectional study and was conducted in Indonesia during the COVID-19 pandemic using an online survey of demographic information and a qualitative questionnaire. Responses were recorded and the association between demographic characteristics from survey questions was tested using chi-square with a risk estimate and 95% confidence interval.
Results: A total of 311 participants from 33 out of 34 provinces in Indonesia participated in this study. Recorded responses showed multiple side effects of the COVID-19 vaccine both short- and long-term experienced by the participants. Significant associations were found between demographic factors and COVID-19 vaccine side effects such as female gender with short-term puncture site (odds ratio [OR], 0.463; 95% confidence interval [CI], 0.263-0.816) and short-term other reactions (OR, 0.463; 95% CI, 0.263-0.816), domicile outside Java island with long-term puncture site (OR, 4.219; 95% CI, 1.401-12.701) and immune reactions (OR, 3.375; 95% CI, 1.356-8.398), also between married marital status and long-term vagal reaction (OR, 4.655; 95% CI, 1.321-16.409).
Conclusion: Gender, domicile and marital status factors were associated with COVID-19 vaccine side effects in Indonesian people.
Keywords: COVID-19; Side effect; Vaccination; Vaccines.