tetano
Editor, Senior Moderator
Emerg Infect Dis. 2012 Jan;18(1):48-56. doi: 10.3201/eid1801.101969.
The 1918-19 influenza pandemic in boyac?, Colombia.
Chowell G, Viboud C, Simonsen L, Miller MA, Acuna-Soto R, D?az JM, Mart?nez-Mart?n AF.
Abstract
To quantify age-specific excess-mortality rates and transmissibility patterns for the 1918-20 influenza pandemic in Boyac?, Colombia, we reviewed archival mortality records. We identified a severe pandemic wave during October 1918-January1919 associated with 40 excess deaths per 10,000 population. The age profile for excess deaths was W shaped; highest mortality rates were among infants (<5 y of age), followed by elderly persons (>60 y) and young adults (25-29 y). Mean reproduction number was estimated at 1.4-1.7, assuming 3- or 4-day generation intervals. Boyac?, unlike cities in Europe, the United States, or Mexico, experienced neither a herald pandemic wave of deaths early in 1918 nor a recrudescent wave in 1920. In agreement with reports from Mexico, our study found no death-sparing effect for elderly persons in Colombia. We found regional disparities in prior immunity and timing of introduction of the 1918 pandemic virus across populations.
PMID:
22257780
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/22257780
The 1918-19 influenza pandemic in boyac?, Colombia.
Chowell G, Viboud C, Simonsen L, Miller MA, Acuna-Soto R, D?az JM, Mart?nez-Mart?n AF.
Abstract
To quantify age-specific excess-mortality rates and transmissibility patterns for the 1918-20 influenza pandemic in Boyac?, Colombia, we reviewed archival mortality records. We identified a severe pandemic wave during October 1918-January1919 associated with 40 excess deaths per 10,000 population. The age profile for excess deaths was W shaped; highest mortality rates were among infants (<5 y of age), followed by elderly persons (>60 y) and young adults (25-29 y). Mean reproduction number was estimated at 1.4-1.7, assuming 3- or 4-day generation intervals. Boyac?, unlike cities in Europe, the United States, or Mexico, experienced neither a herald pandemic wave of deaths early in 1918 nor a recrudescent wave in 1920. In agreement with reports from Mexico, our study found no death-sparing effect for elderly persons in Colombia. We found regional disparities in prior immunity and timing of introduction of the 1918 pandemic virus across populations.
PMID:
22257780
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/22257780