tetano
Editor, Senior Moderator
Glob Chall. 2018 Mar 12;2(4):1700071. doi: 10.1002/gch2.201700071. eCollection 2018 Apr 26. [h=1]Chiral MoS[SUB]2[/SUB] Quantum Dots: Dual-Mode Detection Approaches for Avian Influenza Viruses.[/h]
Ahmed SR[SUP]1[/SUP], Neethirajan S[SUP]1[/SUP].
[h=3]Author information[/h] 1 BioNano Laboratory School of Engineering University of Guelph Guelph Ontario N1G 2W1 Canada.
[h=3]Abstract[/h] Molybdenum disulfide (MoS[SUB]2[/SUB]), a type of transition metal dichalcogenide material, has emerged as an important class among 2D systems. When 2D MoS[SUB]2[/SUB] materials are reduced to 0D quantum dots (QDs), they introduce new optical properties that point to several potential technological advantages in electronic, magnetic, optical, and catalytic properties. In this study, a simple way to produce chiral MoS[SUB]2[/SUB] QDs from MoS[SUB]2[/SUB] nanopowder is presented using l(+)-ascorbic acid as a reducing agent. The calculated quantum yield of QDs is 11.06%. Experimental results reveal that the size of QDs is uniformly monodispersed (2-3 nm) and have a blue emissive fluorescence peak and circular dichroism (CD) peak located at 420 and 330 nm, respectively. Furthermore, a dual-mode detection system based on fluorescence and chirality is performed using as-synthesized MoS[SUB]2[/SUB] QDs, where QDs are conjugated with anti-hemagglutinin antibodies of avian influenza virus and made into an immunobridge in the presence of target virus and anti-neuraminidase antibodies conjugated magnetic nanoparticles (MNPs). The photoluminescence and CD spectra of unconjugated QDs after separated magnetochirofluorescent (MNPs-QDs) nanohybrids by external magnets enables influenza virus A (H5N1) detection with the limit of detection value of 7.35 and 80.92 pg mL[SUP]-1[/SUP], respectively.
? 2018 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim.
[h=4]KEYWORDS:[/h] MoS2 QDs; avian influenza virus; magnetofluorescent nanohybrids; nanosensors
PMID: 31565328 PMCID: PMC6607333 DOI: 10.1002/gch2.201700071
Free PMC Article
Ahmed SR[SUP]1[/SUP], Neethirajan S[SUP]1[/SUP].
[h=3]Author information[/h] 1 BioNano Laboratory School of Engineering University of Guelph Guelph Ontario N1G 2W1 Canada.
[h=3]Abstract[/h] Molybdenum disulfide (MoS[SUB]2[/SUB]), a type of transition metal dichalcogenide material, has emerged as an important class among 2D systems. When 2D MoS[SUB]2[/SUB] materials are reduced to 0D quantum dots (QDs), they introduce new optical properties that point to several potential technological advantages in electronic, magnetic, optical, and catalytic properties. In this study, a simple way to produce chiral MoS[SUB]2[/SUB] QDs from MoS[SUB]2[/SUB] nanopowder is presented using l(+)-ascorbic acid as a reducing agent. The calculated quantum yield of QDs is 11.06%. Experimental results reveal that the size of QDs is uniformly monodispersed (2-3 nm) and have a blue emissive fluorescence peak and circular dichroism (CD) peak located at 420 and 330 nm, respectively. Furthermore, a dual-mode detection system based on fluorescence and chirality is performed using as-synthesized MoS[SUB]2[/SUB] QDs, where QDs are conjugated with anti-hemagglutinin antibodies of avian influenza virus and made into an immunobridge in the presence of target virus and anti-neuraminidase antibodies conjugated magnetic nanoparticles (MNPs). The photoluminescence and CD spectra of unconjugated QDs after separated magnetochirofluorescent (MNPs-QDs) nanohybrids by external magnets enables influenza virus A (H5N1) detection with the limit of detection value of 7.35 and 80.92 pg mL[SUP]-1[/SUP], respectively.
? 2018 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim.
[h=4]KEYWORDS:[/h] MoS2 QDs; avian influenza virus; magnetofluorescent nanohybrids; nanosensors
PMID: 31565328 PMCID: PMC6607333 DOI: 10.1002/gch2.201700071
Free PMC Article