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Human infection with H7N9 avian influenza or a comeback in autumn and winter
2015-08-22 I
China CDC experts said yesterday, for the first time this spring between the body found reassortant bird flu virus H7N9, is likely to stage a comeback in the autumn and winter.
Etiological evidence that when compared to the first six months ago was found in human specimens and, H7N9 virus has changed individual loci. China CDC Viral Disease, an associate researcher at the National Influenza Center Gao Rong Bao reports, the change belongs to small areas, its essence remains the avian virus, yet have effective human transmission capability.
Director of Infectious Diseases at the Chinese Center for Disease Control and Prevention describes Yu Hongjie, China CDC has set up a monitoring network in the country, in all patients with pneumonia of unknown causes in medical institutions, influenza-like illness throughout the 554 sentinel hospitals, the In the 409 influenza network laboratory, around the clock search for traces of H7N9.
In addition, since H7N9 it has been popular, but not the disease among poultry, in a recent emergency meeting of the State Council, has deployed health, forestry, agriculture and other departments to strengthen communication and sharing of relevant information.
Status quo
Have two months no new cases are reported
Gao Rong Bao Description: So far, the country has two months no H7N9 bird flu infection reports.
Yesterday, the Chinese Center for Disease Control Bulletin, as of now, the country reported a total of 134 cases of H7N9 human cases (except case confirmed in Taiwan), 45 deaths, distributed in 70 counties of 12 provinces. Report of 46 cases including Zhejiang, Shanghai reports 33 cases, 80% of Jiangsu 28 cases, three provinces reported cases of the total number of cases. The final report confirmed cases from Guangdong Province, onset time is July 28.
Feature
In close contact with a high probability of pathogenic
Existing epidemiological investigation of reported cases show, H7N9 highly pathogenic avian influenza virus H5N1 than the more easily infect humans, some of its genes, it is easy to combine with the human upper respiratory tract, high Rong Bao said.
In the 134 confirmed cases, significantly more urban residents than rural residents, and the sick, seriously ill to middle-aged male-dominated. Confirmed cases differ from the majority of people live bird markets experience with poultry or close contact exposure. And 5% of people engaged in waders occupation. Many patients have access to a live poultry market, was also detected H7N9 in the agricultural sector.
However, H7N9 is difficult to spread from one person to another person. Only in Shanghai, Beijing found three cases of familial aggregation of cases, experts doubt that it has the ability to spread through the air close.
In addition, experiments in ferrets and other mammals show, H7N9 can spread through the air.
Forecast
Order epidemic complex genetic changes
Gao Rong Bao introduction, animal monitoring found reassortant virus H7N9 has been quietly present it to the birds as the main host, but is not popular among pathogenic avian latency, which makes this year's autumn and winter may be more complicated in the world have come to H7N9 epidemic situation.
Compare the end of March this year, the National Influenza Center isolated from patient specimens in the first strains of H7N9 virus, and early August of this year from the last report of confirmed cases who traced to the H7N9 virus, both of which have changed individual loci Shandong vitiligo, Gao Rong Bao He said that the current H7N9 no significant changes in the nature, is still a source of avian virus through close contact, spread from birds to people.
From past epidemic situation in perspective, H7N9 epidemic has been in a state sporadically, family home of the cases the treatment of vitiligo hospital is only incidental.
Vaccine
Human clinical trials have been carried out
Most people have no immunity to the H7N9 virus common, but do not have an existing influenza vaccine has the ability to make human H7N9 immunization.
Yesterday, Gao Rong Bao introduced for the preparation of the vaccine strain has been distributed to the World Health Organization's global influenza vaccine in many countries manufacturers. Animal experiments have been completed, confirmed the development of an effective vaccine against H7N9 fight.
余宏杰 said the United States already has a research team, began to carry out Phase II H7N9 vaccine clinical trials in humans to confirm the effectiveness of the vaccine.
The experts said, vaccination strategies H7N9 vaccine needs further observation and verification in future outbreaks. (Wei Ming words)
http://www.liaoynews.com/fangchan/16017.shtml
Human infection with H7N9 avian influenza or a comeback in autumn and winter
2015-08-22 I
China CDC experts said yesterday, for the first time this spring between the body found reassortant bird flu virus H7N9, is likely to stage a comeback in the autumn and winter.
Etiological evidence that when compared to the first six months ago was found in human specimens and, H7N9 virus has changed individual loci. China CDC Viral Disease, an associate researcher at the National Influenza Center Gao Rong Bao reports, the change belongs to small areas, its essence remains the avian virus, yet have effective human transmission capability.
Director of Infectious Diseases at the Chinese Center for Disease Control and Prevention describes Yu Hongjie, China CDC has set up a monitoring network in the country, in all patients with pneumonia of unknown causes in medical institutions, influenza-like illness throughout the 554 sentinel hospitals, the In the 409 influenza network laboratory, around the clock search for traces of H7N9.
In addition, since H7N9 it has been popular, but not the disease among poultry, in a recent emergency meeting of the State Council, has deployed health, forestry, agriculture and other departments to strengthen communication and sharing of relevant information.
Status quo
Have two months no new cases are reported
Gao Rong Bao Description: So far, the country has two months no H7N9 bird flu infection reports.
Yesterday, the Chinese Center for Disease Control Bulletin, as of now, the country reported a total of 134 cases of H7N9 human cases (except case confirmed in Taiwan), 45 deaths, distributed in 70 counties of 12 provinces. Report of 46 cases including Zhejiang, Shanghai reports 33 cases, 80% of Jiangsu 28 cases, three provinces reported cases of the total number of cases. The final report confirmed cases from Guangdong Province, onset time is July 28.
Feature
In close contact with a high probability of pathogenic
Existing epidemiological investigation of reported cases show, H7N9 highly pathogenic avian influenza virus H5N1 than the more easily infect humans, some of its genes, it is easy to combine with the human upper respiratory tract, high Rong Bao said.
In the 134 confirmed cases, significantly more urban residents than rural residents, and the sick, seriously ill to middle-aged male-dominated. Confirmed cases differ from the majority of people live bird markets experience with poultry or close contact exposure. And 5% of people engaged in waders occupation. Many patients have access to a live poultry market, was also detected H7N9 in the agricultural sector.
However, H7N9 is difficult to spread from one person to another person. Only in Shanghai, Beijing found three cases of familial aggregation of cases, experts doubt that it has the ability to spread through the air close.
In addition, experiments in ferrets and other mammals show, H7N9 can spread through the air.
Forecast
Order epidemic complex genetic changes
Gao Rong Bao introduction, animal monitoring found reassortant virus H7N9 has been quietly present it to the birds as the main host, but is not popular among pathogenic avian latency, which makes this year's autumn and winter may be more complicated in the world have come to H7N9 epidemic situation.
Compare the end of March this year, the National Influenza Center isolated from patient specimens in the first strains of H7N9 virus, and early August of this year from the last report of confirmed cases who traced to the H7N9 virus, both of which have changed individual loci Shandong vitiligo, Gao Rong Bao He said that the current H7N9 no significant changes in the nature, is still a source of avian virus through close contact, spread from birds to people.
From past epidemic situation in perspective, H7N9 epidemic has been in a state sporadically, family home of the cases the treatment of vitiligo hospital is only incidental.
Vaccine
Human clinical trials have been carried out
Most people have no immunity to the H7N9 virus common, but do not have an existing influenza vaccine has the ability to make human H7N9 immunization.
Yesterday, Gao Rong Bao introduced for the preparation of the vaccine strain has been distributed to the World Health Organization's global influenza vaccine in many countries manufacturers. Animal experiments have been completed, confirmed the development of an effective vaccine against H7N9 fight.
余宏杰 said the United States already has a research team, began to carry out Phase II H7N9 vaccine clinical trials in humans to confirm the effectiveness of the vaccine.
The experts said, vaccination strategies H7N9 vaccine needs further observation and verification in future outbreaks. (Wei Ming words)
http://www.liaoynews.com/fangchan/16017.shtml