Emily
Editor, Senior Moderator
It was part of the workup for a 2002 case in New York where a baby was born with severe birth defects to a woman with West Nile:
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5150a3.htm
Yet this test was not listed as being part of the workup for the babies from Brazil:
http://www.cdc.gov/mmwr/volumes/65/wr/mm6503e2.htm
I'm wondering why since LCMV is said to have a worldwide distribution and must be in South America since a couple of children in a home for the severely disabled in Argentina tested positive for exposure:
www.cfsph.iastate.edu/Factsheets/pdfs/lymphocytic_choriomeningitis.pdf
Periventricular calcifications are found in LCMV and in the Brazil babies:
http://www.thedailybeast.com/articl...brain-damage-worse-than-what-you-re-told.html
https://cid.oxfordjournals.org/content/33/3/370.full
https://pedclerk.bsd.uchicago.edu/page/torch-infections
The mothers in the CDC study were screened to have had rashes, I think, but you can have rashes with LCMV, though it is rarer. But LCMV can also be asymptomatic in mothers who have babies with congenital infections. One of the theories about why Zika may have resulted in uncharacteristic damages in Brazil is that there was a co-infection in those cases.
So I am wondering if there could be an epizootic of LCMV going on in Brazil. Too bad CDC didn't test, but maybe there is a reason they ruled it out without testing. I just hope money was not an issue.
Dr. Tom Frieden @DrFriedenCDC 14h14 hours ago Proposed emergency funds would improve CDC laboratory capacity to test for #Zika, other infectious diseases http://1.usa.gov/1nT3uEm
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5150a3.htm
Yet this test was not listed as being part of the workup for the babies from Brazil:
http://www.cdc.gov/mmwr/volumes/65/wr/mm6503e2.htm
I'm wondering why since LCMV is said to have a worldwide distribution and must be in South America since a couple of children in a home for the severely disabled in Argentina tested positive for exposure:
www.cfsph.iastate.edu/Factsheets/pdfs/lymphocytic_choriomeningitis.pdf
Periventricular calcifications are found in LCMV and in the Brazil babies:
http://www.thedailybeast.com/articl...brain-damage-worse-than-what-you-re-told.html
https://cid.oxfordjournals.org/content/33/3/370.full
https://pedclerk.bsd.uchicago.edu/page/torch-infections
The mothers in the CDC study were screened to have had rashes, I think, but you can have rashes with LCMV, though it is rarer. But LCMV can also be asymptomatic in mothers who have babies with congenital infections. One of the theories about why Zika may have resulted in uncharacteristic damages in Brazil is that there was a co-infection in those cases.
So I am wondering if there could be an epizootic of LCMV going on in Brazil. Too bad CDC didn't test, but maybe there is a reason they ruled it out without testing. I just hope money was not an issue.
Dr. Tom Frieden @DrFriedenCDC 14h14 hours ago Proposed emergency funds would improve CDC laboratory capacity to test for #Zika, other infectious diseases http://1.usa.gov/1nT3uEm